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MTA1 抗体 (C-Term)

This anti-MTA1 antibody is a 兔 多克隆 antibody detecting MTA1 in WB. Suitable for 人, 小鼠, 大鼠, 犬, 豚鼠, 马, 兔 和 Cow.
产品编号 ABIN2780235
发货至: 中国

Quick Overview for MTA1 抗体 (C-Term) (ABIN2780235)

抗原

See all MTA1 抗体
MTA1 (Metastasis Associated 1 (MTA1))

适用

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人, 小鼠, 大鼠, 犬, 豚鼠, 马, 兔, Cow

宿主

  • 44
  • 7
  • 1

克隆类型

  • 45
  • 7
多克隆

标记

  • 39
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This MTA1 antibody is un-conjugated

应用范围

  • 40
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Western Blotting (WB)
  • 抗原表位

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    C-Term

    序列

    MPSRGLANHG QARHMGPSRN LLLNGKSYPT KVRLIRGGSL PPVKRRRMNW

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against MTA1. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human MTA1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 430 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    MTA1 (Metastasis Associated 1 (MTA1))

    别名

    MTA1

    背景

    MTA1 encodes a protein that was identified in a screen for genes expressed in metastatic cells, specifically, mammary adenocarcinoma cell lines. Expression of this gene has been correlated with the metastatic potential of at least two types of carcinomas although it is also expressed in many normal tissues. The role it plays in metastasis is unclear. MTA1 was initially thought to be the 70kD component of a nucleosome remodeling deacetylase complex, NuRD, but it is more likely that this component is a different but very similar protein. These two proteins are so closely related, though, that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. The profile and activity of this gene product suggest that it is involved in regulating transcription and that this may be accomplished by chromatin remodeling.
    Protein Interaction Partner: KRT40, LZTS2, IKZF1, SH3GL1, SAT1, RBBP4, MAGEA11, KPNA3, NOTCH2NL, KRTAP10-8, KHDRBS2, SUMO2, SUMO3, DNMT3B, DNMT1, NACC2, UBC, SUZ12, EED, RNF2, HIC1, SOX2, HDAC2, HDAC1, HIST3H3, GATAD2B, MBD3, KDM1A, POLD3, MTA2, NR2C2, NR2C1, CHD4, UBE2I, HIST2H3C, B
    Protein Size: 430

    分子量

    47 kDa

    基因ID

    9112

    NCBI登录号

    NM_001203258

    途径

    Chromatin Binding
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