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MTA1 抗体 (Middle Region)

MTA1 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, 兔, Cow, 斑马鱼, 山羊 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2780234
发货至: 中国
  • 抗原 See all MTA1 抗体
    MTA1 (Metastasis Associated 1 (MTA1))
    抗原表位
    • 14
    • 11
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 54
    • 25
    • 21
    • 6
    • 6
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠, 犬, 豚鼠, 马, 兔, Cow, 斑马鱼, 山羊
    宿主
    • 47
    • 7
    • 1
    克隆类型
    • 48
    • 7
    多克隆
    标记
    • 38
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MTA1 antibody is un-conjugated
    应用范围
    • 44
    • 27
    • 14
    • 11
    • 9
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    序列
    QQDFLPWKSL TSIIEYYYMW KTTDRYVQQK RLKAAEAESK LKQVYIPNYN
    预测反应
    Cow: 100%, Dog: 100%, Goat: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    产品特性
    This is a rabbit polyclonal antibody against MTA1. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Protein A purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human MTA1
    Top Product
    Discover our top product MTA1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 430 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    MTA1 (Metastasis Associated 1 (MTA1))
    别名
    MTA1 (MTA1 产品)
    别名
    Tex22 antibody, metastasis associated 1 antibody, metastasis associated 1 L homeolog antibody, MTA1 antibody, Mta1 antibody, mta1.L antibody
    背景
    MTA1 encodes a protein that was identified in a screen for genes expressed in metastatic cells, specifically, mammary adenocarcinoma cell lines. Expression of this gene has been correlated with the metastatic potential of at least two types of carcinomas although it is also expressed in many normal tissues. The role it plays in metastasis is unclear. MTA1 was initially thought to be the 70kD component of a nucleosome remodeling deacetylase complex, NuRD, but it is more likely that this component is a different but very similar protein. These two proteins are so closely related, though, that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. The profile and activity of this gene product suggest that it is involved in regulating transcription and that this may be accomplished by chromatin remodeling.
    Protein Interaction Partner: KRT40, LZTS2, IKZF1, SH3GL1, SAT1, RBBP4, MAGEA11, KPNA3, NOTCH2NL, KRTAP10-8, KHDRBS2, SUMO2, SUMO3, DNMT3B, DNMT1, NACC2, UBC, SUZ12, EED, RNF2, HIC1, SOX2, HDAC2, HDAC1, HIST3H3, GATAD2B, MBD3, KDM1A, POLD3, MTA2, NR2C2, NR2C1, CHD4, UBE2I, HIST2H3C, B
    Protein Size: 430
    分子量
    47 kDa
    基因ID
    9112
    NCBI登录号
    NM_001203258
    途径
    Chromatin Binding
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