MEF2C 抗体 (N-Term)
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北京 101111
Quick Overview for MEF2C 抗体 (N-Term) (ABIN2780048)
抗原
See all MEF2C 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- MEF2C Antibody - N-terminal region
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序列
- SRTNSDIVEA LNKKENKGSE SPDPDSSYAL TPRTEEKYKK INEEFDNMIK
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预测反应
- Cow: 86%, Dog: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
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产品特性
- This is a rabbit polyclonal antibody against MEF2C. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of mouse MEF2C
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8105944
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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: "Regulation of multiple transcription factors by reactive oxygen species and effects of pro-inflammatory cytokines released during myocardial infarction on cardiac differentiation of embryonic stem ..." in: International journal of cardiology, Vol. 168, Issue 4, pp. 3458-72, (2013) (PubMed).
: "Induction of cardiomyocyte-like cells in infarct hearts by gene transfer of Gata4, Mef2c, and Tbx5." in: Circulation research, Vol. 111, Issue 9, pp. 1147-56, (2012) (PubMed).
: "Altered expression of the transcription factor Mef2c during retinal degeneration in Rpe65-/- mice." in: Investigative ophthalmology & visual science, Vol. 52, Issue 8, pp. 5933-40, (2011) (PubMed).
: "A purified population of multipotent cardiovascular progenitors derived from primate pluripotent stem cells engrafts in postmyocardial infarcted nonhuman primates." in: The Journal of clinical investigation, Vol. 120, Issue 4, pp. 1125-39, (2010) (PubMed).
: "Genetic fate mapping identifies second heart field progenitor cells as a source of adipocytes in arrhythmogenic right ventricular cardiomyopathy." in: Circulation research, Vol. 104, Issue 9, pp. 1076-84, (2009) (PubMed).
: "Cardiac commitment of primate embryonic stem cells." in: Nature protocols, Vol. 3, Issue 9, pp. 1381-7, (2008) (PubMed).
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- MEF2C (Myocyte Enhancer Factor 2C (MEF2C))
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别名
- MEF2C
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背景
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Background Information: MEF2C is a transcription regulator of slow fiber
Gene Name: Myocyte enhancer factor 2C
Alternative Symbols: Mef2, AV011172, 5430401D19Rik, 9930028G15Rik
Protein Name: Myocyte-specific enhancer factor 2C
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分子量
- 48kDa
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基因ID
- 17260
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NCBI登录号
- NP_079558
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UniProt
- Q8CFN5
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途径
- Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, BCR Signaling
抗原
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