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MEF2C 抗体 (C-Term)

MEF2C 适用: 人, 小鼠 WB, ELISA, IF, IHC (p), ChIP, ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6263204
发货至: 中国
  • 抗原 See all MEF2C 抗体
    MEF2C (Myocyte Enhancer Factor 2C (MEF2C))
    抗原表位
    • 28
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    C-Term
    适用
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    人, 小鼠
    宿主
    • 170
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    克隆类型
    • 173
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    多克隆
    标记
    • 79
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    This MEF2C antibody is un-conjugated
    应用范围
    • 123
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    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Chromatin Immunoprecipitation (ChIP), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    MEF2C Antibody detects endogenous levels of total MEF2C.
    预测反应
    Pig,Horse,Sheep,Dog,Xenopus
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human MEF2C, corresponding to a region within C-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product MEF2C Primary Antibody
  • 应用备注
    IHC 1:50-1:200-P, ChIP, IF/ICC 1:100-1:500, WB 1:500-1:2000, IHC-f 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    MEF2C (Myocyte Enhancer Factor 2C (MEF2C))
    别名
    MEF2C (MEF2C 产品)
    别名
    MEF2C antibody, XMEF2C antibody, si:ch211-202e12.2 antibody, C5DELq14.3 antibody, DEL5q14.3 antibody, 5430401D19Rik antibody, 9930028G15Rik antibody, AV011172 antibody, Mef2 antibody, RGD1563119 antibody, id:ibd5026 antibody, mef2c antibody, wu:fc05b06 antibody, zgc:64184 antibody, zgc:85726 antibody, myocyte enhancer factor 2C antibody, MADS box transcription enhancer factor 2, polypeptide C (myocyte enhancer factor 2C) antibody, myocyte enhancer factor 2cb antibody, MADS box transcription enhancer factor 2, polypeptide C (myocyte enhancer factor 2C) L homeolog antibody, myocyte enhancer factor 2ca antibody, MEF2C antibody, mef2c antibody, mef2cb antibody, mef2c.L antibody, Mef2c antibody, mef2ca antibody
    背景

    Description: Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex. Necessary for proper development of megakaryocytes and platelets and for bone marrow B-lymphopoiesis. Required for B-cell survival and proliferation in response to BCR stimulation, efficient IgG1 antibody responses to T-cell-dependent antigens and for normal induction of germinal center B-cells. May also be involved in neurogenesis and in the development of cortical architecture (By similarity). Isoform 3 and isoform 4, which lack the repressor domain, are more active than isoform 1 and isoform 2.

    Gene: MEF2C

    分子量
    51 kDa
    基因ID
    4208
    UniProt
    Q06413
    途径
    Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, BCR Signaling
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