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IRF5 抗体 (N-Term)

Cited in 1 publication. This 兔 多克隆 anti-IRF5 antibody specifically detects IRF5 in WB. The antibody is reactive with 小鼠 和 大鼠 samples.
产品编号 ABIN2779987
发货至: 中国
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Quick Overview for IRF5 抗体 (N-Term) (ABIN2779987)

抗原

See all IRF5 抗体
IRF5 (Interferon Regulatory Factor 5 (IRF5))

适用

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  • 5
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小鼠, 大鼠

宿主

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  • 9
  • 1
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克隆类型

  • 54
  • 37
多克隆

标记

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This IRF5 antibody is un-conjugated

应用范围

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  • 5
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  • 1
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Western Blotting (WB)
  • 抗原表位

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    N-Term

    序列

    CSNGPAPTES QPTDDYVLGE EEEEEEEELQ RMLPGLSITE PALPGPPNAP

    预测反应

    Mouse: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against IRF5. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of mouse IRF5
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 497 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Takaoka, Yanai, Kondo, Duncan, Negishi, Mizutani, Kano, Honda, Ohba, Mak, Taniguchi: "Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors." in: Nature, Vol. 434, Issue 7030, pp. 243-9, (2005) (PubMed).

  • 抗原

    IRF5 (Interferon Regulatory Factor 5 (IRF5))

    别名

    IRF5

    背景

    The activation of Toll-like receptors (TLRs) is central to innate and adaptive immunity. All TLRs use the adaptor MyD88 for signaling. IRF-5 is generally involved downstream of the TLR-MyD88 signalling pathway for gene induction of proinflammatory cytokines, such as interleukin-6 (IL-6), IL-12 and tumour-necrosis factor-alpha.
    Alias Symbols: mirf5, AW491843
    Protein Interaction Partner: Ubc, Traf6, Irak1, Zfp764, Myd88, Il12b,
    Protein Size: 497

    分子量

    55 kDa

    基因ID

    27056

    NCBI登录号

    NM_012057, NP_036187

    UniProt

    P56477

    途径

    TLR signaling, Autophagy
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