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IRF5 抗体 (N-Term)

This anti-IRF5 antibody is a 兔 多克隆 antibody detecting IRF5 in WB. Suitable for 小鼠 和 大鼠. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2779987
发货至: 中国

Quick Overview for IRF5 抗体 (N-Term) (ABIN2779987)

抗原

See all IRF5 抗体
IRF5 (Interferon Regulatory Factor 5 (IRF5))

适用

  • 70
  • 38
  • 21
  • 6
  • 5
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
小鼠, 大鼠

宿主

  • 66
  • 12
  • 1
  • 1

克隆类型

  • 57
  • 23
多克隆

标记

  • 58
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
This IRF5 antibody is un-conjugated

应用范围

  • 55
  • 32
  • 21
  • 17
  • 14
  • 12
  • 9
  • 6
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 7
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    序列

    CSNGPAPTES QPTDDYVLGE EEEEEEEELQ RMLPGLSITE PALPGPPNAP

    预测反应

    Mouse: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against IRF5. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of mouse IRF5
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 497 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Takaoka, Yanai, Kondo, Duncan, Negishi, Mizutani, Kano, Honda, Ohba, Mak, Taniguchi: "Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors." in: Nature, Vol. 434, Issue 7030, pp. 243-9, (2005) (PubMed).

  • 抗原

    IRF5 (Interferon Regulatory Factor 5 (IRF5))

    别名

    IRF5

    背景

    The activation of Toll-like receptors (TLRs) is central to innate and adaptive immunity. All TLRs use the adaptor MyD88 for signaling. IRF-5 is generally involved downstream of the TLR-MyD88 signalling pathway for gene induction of proinflammatory cytokines, such as interleukin-6 (IL-6), IL-12 and tumour-necrosis factor-alpha.
    Alias Symbols: mirf5, AW491843
    Protein Interaction Partner: Ubc, Traf6, Irak1, Zfp764, Myd88, Il12b,
    Protein Size: 497

    分子量

    55 kDa

    基因ID

    27056

    NCBI登录号

    NM_012057, NP_036187

    UniProt

    P56477

    途径

    TLR signaling, Autophagy
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