TFAM 抗体 (Middle Region)
Quick Overview for TFAM 抗体 (Middle Region) (ABIN2779902)
抗原
See all TFAM 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- SESFQEAKDD SAQGKLKLVN EAWKNLSPEE KQAYIQLAKD DRIRYDNEMK
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预测反应
- Mouse: 100%, Rabbit: 77%, Rat: 93%
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产品特性
- This is a rabbit polyclonal antibody against TFAM. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of mouse TFAM
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 243 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- TFAM (Transcription Factor A, Mitochondrial (TFAM))
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别名
- TFAM
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背景
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TFAM a mitochondrial transcription factor that is a key activator of mitochondrial transcription as well as a participant in mitochondrial genome replication. Studies in mice have demonstrated that this protein is required to regulate the mitochondrial genome copy number and is essential for embryonic development. A mouse model for Kearns Sayre syndrome was produced when expression of the gene was eliminated by targeted disruption in heart and muscle cells.
Alias Symbols: Hmgts, mtTFA, tsHMG, AI661103
Protein Interaction Partner: C1QBP, SNCA,
Protein Size: 243 -
分子量
- 27 kDa
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基因ID
- 21780
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NCBI登录号
- NM_009360, NP_033386
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UniProt
- P40630
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途径
- Chromatin Binding
抗原
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