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HDAC2 抗体 (C-Term)

This anti-HDAC2 antibody is a 兔 多克隆 antibody detecting HDAC2 in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, Cow, 兔, 豚鼠, 犬, 马, Pig 和 Saccharomyces cerevisiae.
产品编号 ABIN2779752
发货至: 中国

Quick Overview for HDAC2 抗体 (C-Term) (ABIN2779752)

抗原

See all HDAC2 抗体
HDAC2 (Histone Deacetylase 2 (HDAC2))

适用

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人, 小鼠, 大鼠, Cow, 兔, 豚鼠, 犬, 马, Pig, Saccharomyces cerevisiae

宿主

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克隆类型

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多克隆

标记

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This HDAC2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    C-Term

    序列

    EEFSDSEDEG EGGRRNVADH KKGAKKARIE EDKKETEDKK TDVKEEDKSK

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 91%

    产品特性

    This is a rabbit polyclonal antibody against HDAC2. It was validated on Western Blot and immunohistochemistry.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human HDAC2
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 488 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    HDAC2 (Histone Deacetylase 2 (HDAC2))

    别名

    HDAC2

    背景

    Histone deacetylase 2 (HDAC2), or transcriptional regulator homolog RPD3 L1, is highly homologous to the yeast transcription factor RPD3 (reduced potassium dependency 3) gene. As in yeast, human HDA2 is likely to be involved in regulating chromatin structure during transcription. It has been implicated to associate with YY1, a mammalian zinc-finger transcription factor, which negatively regulates transcription by tethering RPD3 to DNA as a cofactor. This process is highly concerved from yeast to human.
    Alias Symbols: HD2, RPD3, YAF1
    Protein Interaction Partner: BRCA1, SUMO1, UBC, SMAD7, SMAD2, MXD1, NCOR2, SUMO2, SFPQ, KDM5A, HDAC1, DDB1, CUL4B, CHFR, KDM1A, KDM5B, NFE2L2, PRDM6, DNMT3B, DNMT1, NACC2, HIST1H4A, HIST1H3A, HIST2H2BE, HIST2H2AC, PRDM1, EED, RNF2, SP1, CHD4, CHD3, ACTL6A, C16orf87, HMG20A, HMG20B, C
    Protein Size: 488

    分子量

    55 kDa

    基因ID

    3066

    NCBI登录号

    NM_001527, NP_001518

    UniProt

    Q92769

    途径

    Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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