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WWTR1 抗体 (N-Term)

This anti-WWTR1 antibody is a 兔 多克隆 antibody detecting WWTR1 in WB. Suitable for 人, 小鼠, 大鼠, 犬, Cow, 豚鼠 和 兔.
产品编号 ABIN2779708
发货至: 中国

Quick Overview for WWTR1 抗体 (N-Term) (ABIN2779708)

抗原

See all WWTR1 抗体
WWTR1 (WW Domain Containing Transcription Regulator 1 (WWTR1))

适用

人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔

宿主

  • 29
  • 5

克隆类型

  • 29
  • 5
多克隆

标记

  • 24
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This WWTR1 antibody is un-conjugated

应用范围

  • 27
  • 12
  • 4
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    序列

    PRLAGGAQHV RSHSSPASLQ LGTGAGAAGS PAQQHAHLRQ QSYDVTDELP

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against WWTR1. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human WWTR1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 400 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    WWTR1 (WW Domain Containing Transcription Regulator 1 (WWTR1))

    别名

    WWTR1

    背景

    TAZ (transctiptional coactivator with PDZ-binding motif), also known as WW domain containing transcription regulator 1 (WWTR1), is a member of the bicoid sub-family of homeodomain-containing transcription factors. TAZ is a 14-3-3 binding protein that co-activates Runx2-dependent gene transcription while repressing PPAR-gamma-dependent gene transcription. TAZ has been reported to be a modulator of mesenchymal stem cell differentiation. TAZ may also play a role in brain and sensory organ development. A similar protein in mice is required for proper forebrain development. Two transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants may exist, but their full length sequences have not been determined.
    Alias Symbols: DKFZP586I1419, TAZ
    Protein Interaction Partner: MED28, NOTCH1, YWHAQ, LATS1, BTRC, YWHAE, TP53BP2, PPP1CA, KLF5, YWHAZ, YWHAG, PAX3, SLC9A3R2, TEAD3, TEAD4, NKX2-1, RUNX1,
    Protein Size: 400

    分子量

    44 kDa

    基因ID

    25937

    NCBI登录号

    NM_015472, NP_056287

    UniProt

    Q9GZV5

    途径

    Regulation of Lipid Metabolism by PPARalpha
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