NCOR2 抗体 (N-Term)
Quick Overview for NCOR2 抗体 (N-Term) (ABIN2779658)
抗原
See all NCOR2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- PMPRSSQEEK DEKEKEKEAE KEEEKPEVEN DKEDLLKEKT DDTSGEDNDE
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预测反应
- Cow: 93%, Dog: 86%, Human: 100%, Mouse: 86%, Pig: 100%, Rat: 86%, Yeast: 87%, Zebrafish: 79%
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产品特性
- This is a rabbit polyclonal antibody against NCOR2. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human NCOR2
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anti-Nuclear Receptor Co-Repressor 2 (NCOR2) (AA 670-900) antibody
NCOR2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Co-Repressor 2 (NCOR2) (AA 2201-2525) antibodyNCOR2 适用: 人 ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Co-Repressor 2 (NCOR2) (AA 1-110) antibodyNCOR2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Nuclear Receptor Co-Repressor 2 (NCOR2) (AA 511-560) antibodyNCOR2 适用: 人, 小鼠, 大鼠, Pig, 斑马鱼 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Co-Repressor 2 (NCOR2) (N-Term) antibodyNCOR2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Co-Repressor 2 (NCOR2) (C-Term) antibodyNCOR2 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Co-Repressor 2 (NCOR2) (AA 541-590) antibodyNCOR2 适用: 人, 小鼠, 大鼠, Pig, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Co-Repressor 2 (NCOR2) (AA 511-560) antibodyNCOR2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 2524 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- NCOR2 (Nuclear Receptor Co-Repressor 2 (NCOR2))
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别名
- NCOR2
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背景
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NCOR2 forms a large corepressor complex that contains SIN3A/B and histone deacetylases HDAC1 and HDAC2. This complex associates with the thyroid (TR) and the retinoid acid receptors (RAR) in the absence of ligand, and may stabilize their interaction with TFIIB. NCOR2 mediates the transcriptional repression activity of some nuclear receptors by promoting chromatin condensation, thus preventing access of the basal transcription.Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.
Alias Symbols: SMRT, TRAC, CTG26, SMRTE, TRAC1, N-CoR2, TNRC14, TRAC-1, SMAP270, SMRTE-tau
Protein Interaction Partner: HDAC4, HDAC3, RARA, HMGA1, HDAC2, HDAC1, AURKA, BCL6, BCOR, GPS2, ZBTB16, UBC, E2F1, NR1I2, BTRC, HDAC7, NR1H2, THRA, RUNX1, Pparg, Nr2f1, Nr1i3, Nr2f2, CBX6, C1D, NR1H4, NR1D1, Ppard, SUMO2, CTBP1, ARNT, AHR, NCOR1, AR, NRD1, E2F4, ZBTB7A, SOX2, ESR1, CE
Protein Size: 2524 -
分子量
- 275 kDa
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基因ID
- 9612
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NCBI登录号
- NM_006312, NP_006303
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UniProt
- Q9Y618
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途径
- Notch Signaling, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
抗原
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