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IRF5 抗体 (Middle Region)

Cited in 1 publication. This 兔 多克隆 anti-IRF5 antibody specifically detects IRF5 in WB. The antibody is reactive with 人, 小鼠, 大鼠, Cow, Pig, 兔, 马, 犬, 豚鼠 和 斑马鱼 samples.
产品编号 ABIN2779405
发货至: 中国
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Quick Overview for IRF5 抗体 (Middle Region) (ABIN2779405)

抗原

See all IRF5 抗体
IRF5 (Interferon Regulatory Factor 5 (IRF5))

适用

  • 82
  • 46
  • 30
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
人, 小鼠, 大鼠, Cow, Pig, 兔, 马, 犬, 豚鼠, 斑马鱼

宿主

  • 80
  • 9
  • 1
  • 1

克隆类型

  • 54
  • 37
多克隆

标记

  • 51
  • 6
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 2
  • 2
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This IRF5 antibody is un-conjugated

应用范围

  • 65
  • 33
  • 30
  • 25
  • 21
  • 21
  • 16
  • 5
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    序列

    IFFCFGEEWP DRKPREKKLI TVQVVPVAAR LLLEMFSGEL SWSADSIRLQ

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

    产品特性

    This is a rabbit polyclonal antibody against IRF5. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human IRF5
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 498 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Coletta, Cullington, Clark, Cleland: "Clinical trials update from European Society of Cardiology meeting 2008: TIME-CHF, BACH, BEAUTIFUL, GISSI-HF, and HOME-HF." in: European journal of heart failure, Vol. 10, Issue 12, pp. 1264-7, (2008) (PubMed).

  • 抗原

    IRF5 (Interferon Regulatory Factor 5 (IRF5))

    别名

    IRF5

    背景

    IRF5 is a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Alternative splice variants encoding different isoforms exist. This gene encodes a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Alternative splice variants encoding different isoforms exist.
    Alias Symbols: SLEB10
    Protein Interaction Partner: SGTA, IRF5, COPS7B, COPS4, COPS5, COPS6, COPS8, COPS2, COPS3, UBC, GPS1, TRAF6, MYD88, RGS3, PPM1G, IRF6, HIVEP1, GRB2, CHUK, ALPI, MAVS, GTPBP2, CEP152, GTPBP1, SIN3A, NCOR2, NCOR1, KAT2B, HDAC1, EP300, CREBBP, TRIM15, IKBKE, TBK1, IRF3, XPO1,
    Protein Size: 498

    分子量

    56 kDa

    基因ID

    3663

    NCBI登录号

    NM_032643, NP_116032

    UniProt

    Q13568

    途径

    TLR signaling, Autophagy
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