SUMO1 抗体 (N-Term)
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- 抗原 See all SUMO1 抗体
- SUMO1 (Small Ubiquitin Related Modifier Protein 1 (SUMO1))
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抗原表位
- N-Term
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适用
- 人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马, 兔, 山羊
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SUMO1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- DQEAKPSTED LGDKKEGEYI KLKVIGQDSS EIHFKVKMTT HLKKLKESYC
- 预测反应
- Cow: 100%, Dog: 100%, Goat: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against Sumo1. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- Top Product
- Discover our top product SUMO1 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 101 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- SUMO1 (Small Ubiquitin Related Modifier Protein 1 (SUMO1))
- 别名
- Sumo1 (SUMO1 产品)
- 别名
- DAP1 antibody, GMP1 antibody, OFC10 antibody, PIC1 antibody, SENP2 antibody, SMT3 antibody, SMT3C antibody, SMT3H3 antibody, UBL1 antibody, hm:zeh0670 antibody, wu:fb74c02 antibody, wu:fd12c02 antibody, zgc:65934 antibody, zgc:85634 antibody, SUMO1 antibody, dap1 antibody, gmp1 antibody, ofc10 antibody, pic1 antibody, senp2 antibody, smt3 antibody, smt3c antibody, sumo-1 antibody, sumo1 antibody, ubl1 antibody, xsumo-1 antibody, xsumo1 antibody, ARABIDOPSIS THALIANA SMALL UBIQUITIN-LIKE MODIFIER 1 antibody, ATSUMO1 antibody, F10M23.180 antibody, F10M23_180 antibody, SMALL UBIQUITIN-LIKE MODIFIER 1 antibody, SUM1 antibody, SUMO 1 antibody, small ubiquitin-like modifier 1 antibody, pigSUMO1 antibody, SENTRIN antibody, SMTP3 antibody, SUMO-1 antibody, Smt3C antibody, Ubl1 antibody, small ubiquitin-like modifier 1 antibody, small ubiquitin-like modifier 1 S homeolog antibody, small ubiquitin-related protein 1 antibody, SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) antibody, SMT3 suppressor of mif two 3 homolog 1 (yeast) antibody, small ubiquitin-like modifier 1 L homeolog antibody, Sumo1 antibody, SUMO1 antibody, sumo1 antibody, sumo1.S antibody, sumo-1 antibody, sumo1.L antibody
- 背景
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Ubiquitin-like protein that can be covalently attached to proteins as a monomer or a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by E3 ligases such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. It is involved for instance in targeting RANGAP1 to the nuclear pore complex protein RANBP2. Polymeric SUMO1 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins. It may also regulate a network of genes involved in palate development.
Alias Symbols: GMP1, MGC103203, PIC1, SENTRIN, SMT3, SMT3H3, SMTP3, SUMO-1, Smt3C, Ubl1
Protein Interaction Partner: Pten, Stat1, Pml, Casp8ap2, Traf3, Pik3c3, Npm1, Mdm2, Ube2i, Trp53, Rangap1, Ranbp2, Mthfs, Sox2, Senp2, Rbbp7, Slc1a2, Uimc1, Nfatc2ip, Irf1, Irf8, Smad4, BCL11A, AXIN1, Myb, Pax6, Sept2, Daxx, Sf1, Sp3, Pou5f1, Hif1a, Nfkb2, Junb, Jun,
Protein Size: 101 - 分子量
- 11 kDa
- 基因ID
- 22218
- NCBI登录号
- NM_009460, NP_033486
- UniProt
- P63166
- 途径
- M Phase, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus, Ubiquitin Proteasome Pathway
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