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SUMO1 抗体 (N-Term)

This anti-SUMO1 antibody is a 兔 多克隆 antibody detecting SUMO1 in WB. Suitable for 人, 大鼠, 小鼠, Cow, 犬, 兔, 豚鼠, 马 和 山羊.
产品编号 ABIN2779357
发货至: 中国

Quick Overview for SUMO1 抗体 (N-Term) (ABIN2779357)

抗原

See all SUMO1 抗体
SUMO1 (Small Ubiquitin Related Modifier Protein 1 (SUMO1))

适用

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人, 大鼠, 小鼠, Cow, 犬, 兔, 豚鼠, 马, 山羊

宿主

  • 105
  • 35
  • 3
  • 1
  • 1

克隆类型

  • 95
  • 51
多克隆

标记

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  • 1
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This SUMO1 antibody is un-conjugated

应用范围

  • 117
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  • 15
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Western Blotting (WB)
  • 抗原表位

    • 15
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    N-Term

    序列

    DQEAKPSTED LGDKKEGEYI KLKVIGQDSS EIHFKVKMTT HLKKLKESYC

    预测反应

    Cow: 100%, Dog: 100%, Goat: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against Sumo1. It was validated on Western Blot.

    纯化方法

    Affinity Purified
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 101 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    SUMO1 (Small Ubiquitin Related Modifier Protein 1 (SUMO1))

    别名

    Sumo1

    背景

    Ubiquitin-like protein that can be covalently attached to proteins as a monomer or a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by E3 ligases such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. It is involved for instance in targeting RANGAP1 to the nuclear pore complex protein RANBP2. Polymeric SUMO1 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins. It may also regulate a network of genes involved in palate development.
    Alias Symbols: GMP1, MGC103203, PIC1, SENTRIN, SMT3, SMT3H3, SMTP3, SUMO-1, Smt3C, Ubl1
    Protein Interaction Partner: Pten, Stat1, Pml, Casp8ap2, Traf3, Pik3c3, Npm1, Mdm2, Ube2i, Trp53, Rangap1, Ranbp2, Mthfs, Sox2, Senp2, Rbbp7, Slc1a2, Uimc1, Nfatc2ip, Irf1, Irf8, Smad4, BCL11A, AXIN1, Myb, Pax6, Sept2, Daxx, Sf1, Sp3, Pou5f1, Hif1a, Nfkb2, Junb, Jun,
    Protein Size: 101

    分子量

    11 kDa

    基因ID

    22218

    NCBI登录号

    NM_009460, NP_033486

    UniProt

    P63166

    途径

    M Phase, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus, Ubiquitin Proteasome Pathway
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