FASL 抗体 (Middle Region)
Quick Overview for FASL 抗体 (Middle Region) (ABIN2779355)
抗原
See all FASL 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- MHTASSLEKQ IGHPSPPPEK KELRKVAHLT GKSNSRSMPL EWEDTYGIVL
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预测反应
- Cow: 86%, Horse: 79%, Human: 100%, Pig: 93%, Rabbit: 90%
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产品特性
- This is a rabbit polyclonal antibody against FASLG. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 281 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))
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别名
- FASLG
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背景
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TNFSF6 is a cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T cell mediated apoptosis and in T cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T cells, or both. Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects.
Alias Symbols: APT1LG1, CD178, CD95L, FASL, TNFSF6, CD95-L
Protein Interaction Partner: RGS20, TRIP6, NOTCH2NL, KRT40, FAS, CFLAR, FADD, CASP8, NCF1, MACC1, SH3PXD2B, SNX33, SH3RF2, RIMBP3C, SNX18, EPS8L3, ARHGAP9, SAMSN1, MPP4, SRGAP1, BAIAP2L1, NCKIPSD, SNX9, MYO15A, ITSN2, TJP3, OSTF1, SRGAP2, DNMBP, SORBS3, SRGAP3, DOCK4, SH3PXD2A, KALRN
Protein Size: 281 -
分子量
- 31 kDa
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基因ID
- 356
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NCBI登录号
- NM_000639, NP_000630
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UniProt
- P48023
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途径
- Apoptosis, EGFR Signaling Pathway, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
抗原
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