beta Arrestin 1 抗体 (Middle Region)
Quick Overview for beta Arrestin 1 抗体 (Middle Region) (ABIN2779340)
抗原
See all beta Arrestin 1 (ARRB1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- NETPVDTNLI ELDTNDDDIV FEDFARQRLK GMKDDKEEEE DGTGSPQLNN
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预测反应
- Cow: 90%, Dog: 100%, Horse: 100%, Human: 100%
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产品特性
- This is a rabbit polyclonal antibody against ARRB1. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human ARRB1
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anti-Arrestin, beta 1 (ARRB1) (AA 3-246) antibody
ARRB1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Arrestin, beta 1 (ARRB1) (AA 169-418) antibodyARRB1 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Arrestin, beta 1 (ARRB1) antibodyARRB1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IP, ICC, FACS 宿主: 兔 Monoclonal unconjugated
anti-Arrestin, beta 1 (ARRB1) (AA 336-363), (C-Term) antibodyARRB1 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB31615 unconjugated
anti-Arrestin, beta 1 (ARRB1) (AA 1-260) antibodyARRB1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Arrestin, beta 1 (ARRB1) antibodyARRB1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Arrestin, beta 1 (ARRB1) (AA 369-418) antibodyARRB1 适用: 人 WB, IHC, ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Arrestin, beta 1 (ARRB1) (AA 343-371), (C-Term) antibodyARRB1 适用: 人 WB, IF, IHC (p), FACS, EIA 宿主: 兔 Polyclonal unconjugated
anti-Arrestin, beta 1 (ARRB1) antibodyARRB1 适用: 人, 小鼠, 大鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Arrestin, beta 1 (ARRB1) (Ser157) antibodyARRB1 适用: 人, 猴 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 418 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- beta Arrestin 1 (ARRB1) (Arrestin, beta 1 (ARRB1))
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别名
- ARRB1
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背景
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Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described, however, their exact functions are not known.
Alias Symbols: ARB1, ARR1
Protein Interaction Partner: MAPK9, UBC, PTGER4, SRC, GNMT, NOTCH1, ARRDC1, PTAFR, MAP2K3, LIMK1, PDXP, MAPK14, CLTC, CFL1, AP2A1, MAP3K5, AKT1, AGTR1, MAP2K4, MAPK10, CSK, EDNRA, Agtr1a, NEK6, PIK3R2, NFKBIA, AXIN1, YY1, BTK, BAG1, ADRB1, ADH6, RPL15, PDE4D, Mlnr, Trhr, ARRDC4, ARRD
Protein Size: 418 -
分子量
- 47 kDa
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基因ID
- 408
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NCBI登录号
- NM_004041, NP_004032
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UniProt
- P49407
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途径
- Positive Regulation of Peptide Hormone Secretion, Nuclear Hormone Receptor Binding, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
抗原
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