Crk 抗体 (C-Term)
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Quick Overview for Crk 抗体 (C-Term) (ABIN2779332)
抗原
See all Crk (CRK) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- IPVPYVEKYR PASASVSALI GGNQEGSHPQ PLGGPEPGPY AQPSVNTPLP
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against CRK. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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anti-V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK) antibody
CRK 适用: 人 ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 3G11C1 unconjugated
anti-V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK) (pTyr221) antibodyCRK 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK) (AA 1-204) antibodyCRK 适用: 人 WB, IF, PLA 宿主: 兔 Polyclonal unconjugated
anti-V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK) (AA 2-246) antibodyCRK 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK) antibodyKD Validated CRK 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB1405 unconjugated Recombinant Antibody
anti-V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK) (AA 1-204) antibodyCRK 适用: 人 WB, PLA 宿主: 小鼠 Polyclonal unconjugated
anti-V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK) (AA 122-302) antibodyCRK 适用: 人, 小鼠 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK) (Center) antibodyCRK 适用: 人, 小鼠 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK) (pTyr221) antibodyCRK 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK) (AA 1-304) antibodyCRK 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 304 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Crk (CRK) (V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK))
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别名
- CRK
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背景
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This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described.
Alias Symbols: CRKII, p38
Protein Interaction Partner: FAM154A, HUWE1, ABL2, ABL1, SPRR2A, MET, CBL, BAG3, LMNA, ERBB3, ERBB2, EGFR, PPFIBP2, ATXN1, PTPN4, MAPK4, DOK1, BCAR1, NANS, FUBP1, SPR, HSPB1, DHX9, SERPINH1, ATIC, PIK3R2, PIK3R1, PIK3CD, PIK3CB, PIK3CA, PIK3C2B, SERPINB6, LYZ, KRT19, KRT17, KRT16, KR
Protein Size: 304 -
分子量
- 34 kDa
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基因ID
- 1398
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NCBI登录号
- NM_016823, NP_058431
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UniProt
- P46108
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途径
- Neurotrophin Signaling Pathway, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor
抗原
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