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AKT2 抗体 (Middle Region)

AKT2 适用: 人, 小鼠, 大鼠, 犬, Cow, Pig, 马, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2779323
发货至: 中国
  • 抗原 See all AKT2 抗体
    AKT2 (V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2))
    抗原表位
    • 21
    • 21
    • 15
    • 15
    • 15
    • 15
    • 8
    • 7
    • 7
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 176
    • 102
    • 67
    • 15
    • 15
    • 13
    • 12
    • 12
    • 11
    • 10
    • 10
    • 10
    • 7
    • 3
    • 3
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠, 犬, Cow, Pig, 马, 斑马鱼
    宿主
    • 156
    • 27
    • 5
    • 2
    • 1
    • 1
    克隆类型
    • 158
    • 32
    多克隆
    标记
    • 95
    • 15
    • 15
    • 10
    • 8
    • 8
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This AKT2 antibody is un-conjugated
    应用范围
    • 161
    • 100
    • 67
    • 35
    • 28
    • 27
    • 26
    • 17
    • 17
    • 10
    • 8
    • 8
    • 7
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    TSEVDTRYFD DEFTAQSITI TPPDRYDSLG LLELDQRTHF PQFSYSASIR
    预测反应
    Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%, Zebrafish: 100%
    产品特性
    This is a rabbit polyclonal antibody against AKT2. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human AKT2
    Top Product
    Discover our top product AKT2 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 481 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Tan, Timakhov, Rao, Altomare, Xu, Liu, Gao, Jhanwar, Di Cristofano, Wiest, Knepper, Testa: "A novel recurrent chromosomal inversion implicates the homeobox gene Dlx5 in T-cell lymphomas from Lck-Akt2 transgenic mice." in: Cancer research, Vol. 68, Issue 5, pp. 1296-302, (2008) (PubMed).

  • 抗原
    AKT2 (V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2))
    别名
    AKT2 (AKT2 产品)
    别名
    AKT2 antibody, pkbb antibody, pkbbeta antibody, pkbss antibody, prkbb antibody, rac-beta antibody, v-akt2 antibody, 2410016A19Rik antibody, AW554154 antibody, PKB antibody, PKBbeta antibody, HIHGHH antibody, PKBB antibody, PKBBETA antibody, PRKBB antibody, RAC-BETA antibody, cb945 antibody, akt2-a antibody, AKT serine/threonine kinase 2 antibody, v-akt murine thymoma viral oncogene homolog 2 antibody, thymoma viral proto-oncogene 2 antibody, v-akt murine thymoma viral oncogene homolog 2 L homeolog antibody, AKT2 antibody, akt2 antibody, Akt2 antibody, akt2.L antibody
    背景
    AKT2 belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene encoding AKT2 was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. AKT2 is a general protein kinase capable of phophorylating several known proteins.This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: PKBBETA, PRKBB, RAC-BETA, PKBB, HIHGHH
    Protein Interaction Partner: CLIP3, CHUK, PLEKHO1, PRKCZ, UBC, EGFR, POLR1B, SNX27, PNPLA3, STEAP4, ABCG8, POFUT1, TMED2, NAMPT, SORBS2, SPRR2A, CCL14, PRKDC, MAP3K5, HSP90AA1, APOB, APOA1, APPL1, APP, FSHR, VIM, SKI, GRK5, SH3RF1, ESR1, TTC3, SETDB1, XIAP, AKT1S1, TRIB3, PDPK1, GSK3
    Protein Size: 481
    分子量
    56 kDa
    基因ID
    208
    NCBI登录号
    NM_001626, NP_001617
    UniProt
    P31751
    途径
    PI3K-Akt Signaling, RTK signaling, AMPK Signaling, TLR signaling, Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Hepatitis C, VEGF Signaling
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