FADD 抗体 (C-Term)
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Quick Overview for FADD 抗体 (C-Term) (ABIN309589)
抗原
See all FADD 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- ASVAGLVKAL RTCRLNLVAD LVEEAQESVS KSENMSPVLR DSTVSSSETP
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预测反应
- Mouse: 100%
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产品特性
- This is a rabbit polyclonal antibody against Fadd. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of mouse FADD
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anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 12-206) antibody
FADD 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 1-208) antibodyFADD 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 20-150) antibodyFADD 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 5A6A2 unconjugated
anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 7-178) antibodyFADD 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 109-208) antibodyFADD 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3C3 unconjugated
anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 1-208) antibodyFADD 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) antibodyFADD 适用: 小鼠 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 1-208) antibodyFADD 适用: 人 WB, IHC, ELISA, IF, ICC 宿主: 小鼠 Monoclonal J1D2 unconjugated
anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 1-80) antibodyFADD 适用: 人, 小鼠, 大鼠, 猴, Pig WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 1-208) antibodyFADD 适用: 人 WB, IHC, ELISA 宿主: 小鼠 Monoclonal J1D2 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 205 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))
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别名
- FADD
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背景
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Fadd is apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis.
Alias Symbols: Mort1/FADD
Protein Interaction Partner: Atg16l1, Atg7, Atg12, Map1lc3a, Ripk1, Casp8, Atg5, Fas, Pidd1, Cflar, Tnf, Nol3,
Protein Size: 205 -
分子量
- 23 kDa
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基因ID
- 14082
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NCBI登录号
- NM_010175, NP_034305
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UniProt
- Q61160
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途径
- Apoptosis, TLR signaling, Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades
抗原
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