FADD 抗体 (C-Term)
-
- 抗原 See all FADD 抗体
- FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))
-
抗原表位
- C-Term
-
适用
- 小鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This FADD antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 序列
- ASVAGLVKAL RTCRLNLVAD LVEEAQESVS KSENMSPVLR DSTVSSSETP
- 预测反应
- Mouse: 100%
- 产品特性
- This is a rabbit polyclonal antibody against Fadd. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of mouse FADD
- Top Product
- Discover our top product FADD Primary Antibody
-
-
- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
-
Antigen size: 205 AA
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- 抗原
- FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))
- 别名
- FADD (FADD 产品)
- 别名
- MORT1 antibody, Mort1/FADD antibody, Mort1 antibody, TNFRSF6 antibody, adaptor antibody, fadd antibody, mort1 antibody, xfadd antibody, Fas associated via death domain antibody, Fas (TNFRSF6)-associated via death domain antibody, Fas associated via death domain S homeolog antibody, Fas (tnfrsf6)-associated via death domain antibody, FADD antibody, Fadd antibody, fadd.S antibody, fadd antibody
- 背景
-
Fadd is apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis.
Alias Symbols: Mort1/FADD
Protein Interaction Partner: Atg16l1, Atg7, Atg12, Map1lc3a, Ripk1, Casp8, Atg5, Fas, Pidd1, Cflar, Tnf, Nol3,
Protein Size: 205 - 分子量
- 23 kDa
- 基因ID
- 14082
- NCBI登录号
- NM_010175, NP_034305
- UniProt
- Q61160
- 途径
- Apoptosis, TLR signaling, Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades
-