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HSP27 抗体 (C-Term)

Cited in 2+ publications. This 兔 多克隆 anti-HSP27 antibody specifically detects HSP27 in WB 和 IHC. The antibody is reactive with 人 samples.
产品编号 ABIN2779293
发货至: 中国
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Quick Overview for HSP27 抗体 (C-Term) (ABIN2779293)

抗原

See all HSP27 (HSPB1) 抗体
HSP27 (HSPB1) (Heat Shock 27kDa Protein 1 (HSPB1))

适用

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宿主

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多克隆

标记

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This HSP27 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
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    C-Term

    序列

    SLSPEGTLTV EAPMPKLATQ SNEITIPVTF ESRAQLGGPE AAKSDETAAK

    预测反应

    Human: 100%

    产品特性

    This is a rabbit polyclonal antibody against HSPB1. It was validated on Western Blot and immunohistochemistry.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human HSPB1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 205 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Sookoian, Castaño, Scian, San Martino, Pirola: "Heat Shock Protein 27 is down-regulated in Ballooned Hepatocytes of Patients with Nonalcoholic Steatohepatitis (NASH)." in: Scientific reports, Vol. 6, pp. 22528, (2016) (PubMed).

    Narjoz, Marisa, Imbeaud, Paris, Delacroix, Beaune, De Waziers: "Genomic consequences of cytochrome P450 2C9 overexpression in human hepatoma cells." in: Chemical research in toxicology, Vol. 22, Issue 5, pp. 779-87, (2009) (PubMed).

  • 抗原

    HSP27 (HSPB1) (Heat Shock 27kDa Protein 1 (HSPB1))

    别名

    HSPB1

    背景

    HSPB1, like the other heat shock proteins, is part of a complex system of molecular chaperones in epidermal keratinocytes.
    Alias Symbols: CMT2F, DKFZp586P1322, HS.76067, HSP27, HSP28, Hsp25, HMN2B, SRP27
    Protein Interaction Partner: PCSK9, HUWE1, UBC, GATA1, MAPKAPK2, AKT1, CRYAB, MAP3K7, SUMO2, HAUS1, CEP57, AARSD1, BAG3, IRS4, HSF1, LCE3A, TGFB1I1, SUMO1, NEDD8, MDM2, ASB6, ASB10, ASB17, WWOX, ASB4, ZBTB1, RPA3, RPA2, RPA1, EZH2, ESR1, SOX2, NPM1, PLG, CS, MAPKAPK3, INS, HSPB1, SGA
    Protein Size: 205

    分子量

    23 kDa

    基因ID

    3315

    NCBI登录号

    NM_001540, NP_001531

    UniProt

    P04792

    途径

    MAPK Pathway, Regulation of Actin Filament Polymerization, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of intrinsic apoptotic Signaling, VEGF Signaling
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