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PTBP1 抗体 (N-Term)

Name: PTBP1 抗体 (N-Term)
SKU: ABIN2778814
Availability: OutOfStock

This anti-PTBP1 antibody is a 兔多克隆 antibody detecting PTBP1 in WB. Suitable for 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔和斑马鱼.

WB Suggested Anti-PTBP1 Antibody Titration: 0. (PTBP1 抗体 (N-Term))

Host: Rabbit Target Name: PTBP1 Sample Tissue: Human HepG2 Antibody Dilution: 1. (PTBP1 抗体 (N-Term))

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产品编号 ABIN2778814

发货至: 中国

Datasheet as PDF

Quick Overview for PTBP1 抗体 (N-Term) (ABIN2778814)

抗原

See all PTBP1 抗体

PTBP1 (Polypyrimidine Tract Binding Protein 1 (PTBP1))

适用

人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼

宿主

兔

克隆类型

多克隆

标记

This PTBP1 antibody is un-conjugated

应用范围

Western Blotting (WB)

Discover our top product PTBP1 Primary Antibody

抗原表位
8

5

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3

3

2

2

2

1

1

1

1

1
N-Term

序列

RGSDELFSTC VTNGPFIMSS NSASAANGND SKKFKGDSRS AGVPSRVIHI

预测反应

Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 91%, Rat: 100%, Zebrafish: 93%

产品特性

This is a rabbit polyclonal antibody against PTBP1. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the N terminal region of human PTBP1
anti-Polypyrimidine Tract Binding Protein 1 (PTBP1) (AA 45-144) antibody
PTBP1 适用: 人 WB, ELISA, IF, IP, IHC (p) 宿主: 小鼠 Monoclonal 3H8 unconjugated

anti-Polypyrimidine Tract Binding Protein 1 (PTBP1) (N-Term) antibody
Verified PTBP1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated

anti-Polypyrimidine Tract Binding Protein 1 (PTBP1) (AA 1-100) antibody
PTBP1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Polypyrimidine Tract Binding Protein 1 (PTBP1) (AA 1-290) antibody
PTBP1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Polypyrimidine Tract Binding Protein 1 (PTBP1) antibody
PTBP1 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated

anti-Polypyrimidine Tract Binding Protein 1 (PTBP1) antibody
PTBP1 适用: 人 WB, IHC, ELISA 宿主: 兔 Monoclonal 8A1 unconjugated Recombinant Antibody

anti-Polypyrimidine Tract Binding Protein 1 (PTBP1) (N-Term) antibody
PTBP1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Polypyrimidine Tract Binding Protein 1 (PTBP1) (AA 26-55), (N-Term) antibody
PTBP1 适用: 人 WB 宿主: 兔 Polyclonal RB40967 unconjugated

anti-Polypyrimidine Tract Binding Protein 1 (PTBP1) (AA 1-557) antibody
PTBP1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated

anti-Polypyrimidine Tract Binding Protein 1 (PTBP1) (AA 45-145) antibody
PTBP1 适用: 人 WB, IHC, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 3H8 unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 531 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
抗原

PTBP1 (Polypyrimidine Tract Binding Protein 1 (PTBP1))

别名

PTBP1

背景

PTBP1 belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA-binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. This protein binds to the intronic polypyrimidine tracts that requires pre-mRNA splicing and acts via the protein degradation ubiquitin-proteasome pathway. It may also promote the binding of U2 snRNP to pre-mRNAs.This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA-binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has four repeats of quasi-RNA recognition motif (RRM) domains that bind RNAs. This protein binds to the intronic polypyrimidine tracts that requires pre-mRNA splicing and acts via the protein degradation ubiquitin-proteasome pathway. It may also promote the binding of U2 snRNP to pre-mRNAs. This protein is localized in the nucleoplasm and it is also detected in the perinucleolar structure. Alternatively spliced transcript variants encoding different isoforms have been described.
Alias Symbols: HNRNPI, HNRPI, MGC10830, MGC8461, PTB, PTB-1, PTB-T, PTB2, PTB3, PTB4, pPTB, HNRNP-I
Protein Interaction Partner: UBC, SNRPA, SFPQ, PTBP1, NONO, LGR4, MDM2, RPA3, RPA2, RPA1, BMI1, SUZ12, EED, RNF2, DIMT1, YBX3, AIMP2, SPTAN1, RPS27, QARS, YBX1, RPSA, ILF2, HNRNPU, HNRNPD, HNRNPA2B1, FAU, EPRS, EIF4G1, APBB1, ABCF1, NELFB, G3BP1, AIMP1, EIF2B2, IQGAP1, TARDBP, SRPK2,
Protein Size: 531

分子量

58 kDa

基因ID

5725

NCBI登录号

NM_031991, NP_114368

UniProt

P26599

途径

Regulation of Muscle Cell Differentiation