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CREB1 抗体 (Middle Region)

This anti-CREB1 antibody is a 兔 多克隆 antibody detecting CREB1 in WB. Suitable for 人, 小鼠, 大鼠, 斑马鱼, Cow, 绵羊, 犬, 马, 兔 和 豚鼠.
产品编号 ABIN2778454
发货至: 中国

Quick Overview for CREB1 抗体 (Middle Region) (ABIN2778454)

抗原

See all CREB1 抗体
CREB1 (cAMP Responsive Element Binding Protein 1 (CREB1))

适用

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人, 小鼠, 大鼠, 斑马鱼, Cow, 绵羊, 犬, 马, 兔, 豚鼠

宿主

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克隆类型

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多克隆

标记

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This CREB1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    Middle Region

    序列

    TYQIRTAPTS TIAPGVVMAS SPALPTQPAE EAARKREVRL MKNREAAREC

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 86%

    产品特性

    This is a rabbit polyclonal antibody against CREB1. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human CREB1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 341 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    CREB1 (cAMP Responsive Element Binding Protein 1 (CREB1))

    别名

    CREB1

    背景

    CREB1 is a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in two transcript variants encoding different isoforms.
    Alias Symbols: CREB, MGC9284
    Protein Interaction Partner: UBC, NCOR1, CREM, CREBBP, RPS6KA1, NR5A2, EP300, DEAF1, TP53, CREB1, PRKG1, YAP1, MAPK14, MEIS1, DAXX, TSSK4, AKT1, ATR, SIRT1, SRA1, DR1, ATF7, GSK3B, GSK3A, ATXN3, DNMT3B, RPS6KA5, YY1, RGS13, JUN, HDAC2, HDAC1, CCDC6, PPP1CA, SUMO1, TAF4, POU2F1, MYOD1
    Protein Size: 341

    分子量

    37 kDa

    基因ID

    1385

    NCBI登录号

    NM_134442, NP_604391

    UniProt

    P16220

    途径

    TLR signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Regulation of Cell Size, Toll-Like Receptors Cascades, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Positive Regulation of fat Cell Differentiation
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