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Kallikrein 6 抗体 (N-Term)

This anti-Kallikrein 6 antibody is a 兔 多克隆 antibody detecting Kallikrein 6 in WB 和 IHC. Suitable for 人, 犬 和 马.
产品编号 ABIN2778179
发货至: 中国

Quick Overview for Kallikrein 6 抗体 (N-Term) (ABIN2778179)

抗原

See all Kallikrein 6 (KLK6) 抗体
Kallikrein 6 (KLK6)

适用

  • 45
  • 20
  • 14
  • 2
人, 犬, 马

宿主

  • 67
  • 7
  • 2

克隆类型

  • 69
  • 7
多克隆

标记

  • 36
  • 12
  • 9
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Kallikrein 6 antibody is un-conjugated

应用范围

  • 61
  • 33
  • 22
  • 20
  • 13
  • 13
  • 10
  • 9
  • 8
  • 5
  • 5
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 15
    • 7
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    序列

    KHNLRQRESS QEQSSVVRAV IHPDYDAASH DQDIMLLRLA RPAKLSELIQ

    预测反应

    Dog: 92%, Horse: 92%, Human: 100%

    产品特性

    This is a rabbit polyclonal antibody against KLK6. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human KLK6
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 244 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    Kallikrein 6 (KLK6)

    别名

    KLK6

    背景

    Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. The gene that encodes KLK6 protein is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. KLK6 is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease.Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease. Multiple alternatively spliced transcript variants that encode different isoforms have been identified for this gene.
    Alias Symbols: Bssp, Klk7, MGC9355, NEUROSIN, PRSS18, PRSS9, SP59, ZYME, hK6
    Protein Interaction Partner: SNCA, SERPINF2, SERPINC1,
    Protein Size: 244

    分子量

    25 kDa

    基因ID

    5653

    NCBI登录号

    NM_001012964, NP_001012982

    UniProt

    Q92876

    途径

    Complement System, Regulation of G-Protein Coupled Receptor Protein Signaling
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