PARP2 抗体 (Middle Region)
Quick Overview for PARP2 抗体 (Middle Region) (ABIN2778112)
抗原
See all PARP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- LLDLFEVEKD GEKEAFREDL HNRMLLWHGS RMSNWVGILS HGLRIAHPEA
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预测反应
- Cow: 86%, Dog: 86%, Guinea Pig: 92%, Horse: 86%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 92%
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产品特性
- This is a rabbit polyclonal antibody against PARP2. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human PARP2
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 534 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PARP2 (Poly (ADP-Ribose) Polymerase 2 (PARP2))
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别名
- PARP2
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背景
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PARP2 contains a catalytic domain and is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. The basic residues within the N-terminal region of this protein may bear potential DNA-binding properties, and may be involved in the nuclear and/or nucleolar targeting of protein.
Alias Symbols: ADPRT2, PARP-2, ADPRTL2, ADPRTL3, pADPRT-2
Protein Interaction Partner: UHRF1, Npm1, TFAP4, UBC, RNF146, H3F3A, CBX5, TRIM28, CHD1L, TNP2, HSPA2, BUB3, CASP8, XRCC1, PARP1, CENPB, CENPA,
Protein Size: 534 -
分子量
- 61 kDa
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基因ID
- 10038
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NCBI登录号
- NM_005484, NP_005475
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UniProt
- Q9UGN5
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途径
- DNA Damage Repair
抗原
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