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BMI1 抗体 (Middle Region)

BMI1 适用: 人, 小鼠, 大鼠, 兔, 犬, Cow, 马, 豚鼠, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2778059
发货至: 中国
  • 抗原 See all BMI1 抗体
    BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))
    抗原表位
    • 14
    • 8
    • 7
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 109
    • 46
    • 25
    • 10
    • 6
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 兔, 犬, Cow, 马, 豚鼠, 斑马鱼
    宿主
    • 76
    • 31
    • 6
    克隆类型
    • 77
    • 36
    多克隆
    标记
    • 76
    • 8
    • 8
    • 5
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BMI1 antibody is un-conjugated
    应用范围
    • 90
    • 49
    • 40
    • 20
    • 14
    • 13
    • 11
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    MDIPNTFQID VMYEEEPLKD YYTLMDIAYI YTWRRNGPLP LKYRVRPTCK
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%, Zebrafish: 77%
    产品特性
    This is a rabbit polyclonal antibody against Bmi1. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    Top Product
    Discover our top product BMI1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 324 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))
    别名
    Bmi1 (BMI1 产品)
    别名
    FLVI2/BMI1 antibody, PCGF4 antibody, RNF51 antibody, AW546694 antibody, Bmi-1 antibody, Pcgf4 antibody, bmi1 antibody, pcgf4 antibody, psc1 antibody, wu:fb17g03 antibody, wu:fd18f06 antibody, BMI-1 antibody, pcgf4b antibody, bmi-1 antibody, bmi1-a antibody, bmi1-b antibody, bmi1b antibody, rnf51 antibody, xbmi-1 antibody, BMI1 proto-oncogene, polycomb ring finger antibody, BMI1 polycomb ring finger oncogene antibody, Bmi1 polycomb ring finger oncogene antibody, bmi1 polycomb ring finger oncogene 1a antibody, bmi1 polycomb ring finger oncogene 1b antibody, BMI1 proto-oncogene, polycomb ring finger L homeolog antibody, BMI1 antibody, LOC100230513 antibody, Bmi1 antibody, bmi1a antibody, bmi1b antibody, bmi1.L antibody
    背景
    Bmi1 is a component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
    Alias Symbols: AW546694, Bmi-1, Pcgf4
    Protein Interaction Partner: Rnf2, Eed, Aurkb, Phc2, RING1, Gata6, Mph1, Cbfb, Runx1, Cdkn2a, HIST2H2AC, Slc11a1, Dnmt3b, Kdm2b, Phc1, Cbx2, Phc3, Dmap1, CBX8, SCMH1, CBX4, SMARCA5, HSPA4,
    Protein Size: 324
    分子量
    37 kDa
    基因ID
    12151
    NCBI登录号
    NM_007552, NP_031578
    UniProt
    P25916
    途径
    Cell Division Cycle, Autophagy
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