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BMI1 抗体 (Middle Region)

This anti-BMI1 antibody is a 兔 多克隆 antibody detecting BMI1 in WB. Suitable for 人, 小鼠, 大鼠, 兔, 犬, Cow, 马, 豚鼠 和 斑马鱼.
产品编号 ABIN2778059
发货至: 中国

Quick Overview for BMI1 抗体 (Middle Region) (ABIN2778059)

抗原

See all BMI1 抗体
BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))

适用

  • 138
  • 54
  • 27
  • 9
  • 7
  • 6
  • 6
  • 6
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠, 兔, 犬, Cow, 马, 豚鼠, 斑马鱼

宿主

  • 78
  • 58
  • 6

克隆类型

  • 78
  • 64
多克隆

标记

  • 86
  • 11
  • 8
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This BMI1 antibody is un-conjugated

应用范围

  • 108
  • 74
  • 44
  • 32
  • 30
  • 17
  • 12
  • 12
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 38
    • 9
    • 7
    • 6
    • 6
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    序列

    MDIPNTFQID VMYEEEPLKD YYTLMDIAYI YTWRRNGPLP LKYRVRPTCK

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%, Zebrafish: 77%

    产品特性

    This is a rabbit polyclonal antibody against Bmi1. It was validated on Western Blot.

    纯化方法

    Affinity Purified
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 324 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))

    别名

    Bmi1

    背景

    Bmi1 is a component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
    Alias Symbols: AW546694, Bmi-1, Pcgf4
    Protein Interaction Partner: Rnf2, Eed, Aurkb, Phc2, RING1, Gata6, Mph1, Cbfb, Runx1, Cdkn2a, HIST2H2AC, Slc11a1, Dnmt3b, Kdm2b, Phc1, Cbx2, Phc3, Dmap1, CBX8, SCMH1, CBX4, SMARCA5, HSPA4,
    Protein Size: 324

    分子量

    37 kDa

    基因ID

    12151

    NCBI登录号

    NM_007552, NP_031578

    UniProt

    P25916

    途径

    Cell Division Cycle, Autophagy
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