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Claudin 1 抗体 (C-Term)

This anti-Claudin 1 antibody is a 兔 多克隆 antibody detecting Claudin 1 in WB 和 IHC. Suitable for 人, 大鼠, 小鼠, 犬, Cow, 绵羊, 兔, 豚鼠 和 马. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2778045
发货至: 中国

Quick Overview for Claudin 1 抗体 (C-Term) (ABIN2778045)

抗原

See all Claudin 1 (CLDN1) 抗体
Claudin 1 (CLDN1)

适用

  • 100
  • 55
  • 53
  • 21
  • 13
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
人, 大鼠, 小鼠, 犬, Cow, 绵羊, 兔, 豚鼠, 马

宿主

  • 94
  • 12

克隆类型

  • 92
  • 14
多克隆

标记

  • 55
  • 6
  • 5
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
This Claudin 1 antibody is un-conjugated

应用范围

  • 81
  • 40
  • 33
  • 24
  • 17
  • 15
  • 15
  • 14
  • 13
  • 11
  • 4
  • 3
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 16
    • 14
    • 8
    • 7
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    序列

    GQALFTGWAA ASLCLLGGAL LCCSCPRKTT SYPTPRPYPK PAPSSGKDYV

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Sheep: 100%

    产品特性

    This is a rabbit polyclonal antibody against CLDN1. It was validated on Western Blot and immunohistochemistry.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human CLDN1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 211 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Coyne, Gambling, Boucher, Carson, Johnson: "Role of claudin interactions in airway tight junctional permeability." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 285, Issue 5, pp. L1166-78, (2003) (PubMed).

  • 抗原

    Claudin 1 (CLDN1)

    别名

    CLDN1

    背景

    Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This protein, a member of the claudin family, is an integral membrane protein and a component of tight junction strands.
    Alias Symbols: CLD1, SEMP1, ILVASC
    Protein Interaction Partner: UBC, DRG1, LNX1, TJP3, BRD4, MPDZ, TJP2, CLDN1, INADL, CLDN3, WNK4, TJP1, MMP14, MMP2, CLDN5,
    Protein Size: 211

    分子量

    23 kDa

    基因ID

    9076

    NCBI登录号

    NM_021101, NP_066924

    UniProt

    O95832

    途径

    Cell-Cell Junction Organization, Hepatitis C
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