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SNAIL 抗体 (N-Term)

This anti-SNAIL antibody is a 兔 多克隆 antibody detecting SNAIL in WB 和 IHC. Suitable for 人, 小鼠, 大鼠 和 豚鼠. This Primary Antibody has been cited in 4+ publications.
产品编号 ABIN2777858
发货至: 中国

Quick Overview for SNAIL 抗体 (N-Term) (ABIN2777858)

抗原

See all SNAIL (SNAI1) 抗体
SNAIL (SNAI1)

适用

  • 87
  • 37
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  • 1
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人, 小鼠, 大鼠, 豚鼠

宿主

  • 72
  • 13
  • 3
  • 2

克隆类型

  • 77
  • 13
多克隆

标记

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  • 2
  • 2
  • 2
  • 2
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  • 1
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This SNAIL antibody is un-conjugated

应用范围

  • 68
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  • 7
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  • 3
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  • 2
  • 1
  • 1
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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 13
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    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
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    N-Term

    序列

    MPRSFLVRKP SDPNRKPNYS ELQDSNPEFT FQQPYDQAHL LAAIPPPEIL

    预测反应

    Guinea Pig: 100%, Human: 100%, Mouse: 93%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against SNAI1. It was validated on Western Blot and immunohistochemistry.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human SNAI1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 264 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • He, Lu, Hu, Zhang, Qin, Wang, Xing, Xi, Wang: "The Wnt11 Signaling Pathway in Potential Cellular EMT and Osteochondral Differentiation Progression in Nephrolithiasis Formation." in: International journal of molecular sciences, Vol. 16, Issue 7, pp. 16313-29, (2016) (PubMed).

    Sihto, Lundin, Lundin, Lehtimäki, Ristimäki, Holli, Sailas, Kataja, Turpeenniemi-Hujanen, Isola, Heikkilä, Joensuu: "Breast cancer biological subtypes and protein expression predict for the preferential distant metastasis sites: a nationwide cohort study." in: Breast cancer research : BCR, Vol. 13, Issue 5, pp. R87, (2012) (PubMed).

    Surati, Robinson, Nandi, Faoro, Demchuk, Rolle, Kanteti, Ferguson, Hasina, Gangadhar, Salama, Arif, Kirchner, Mendonca, Campbell, Limvorasak, Villaflor, Hensing, Krausz, Vokes, Husain, Ferguson et al.: "Proteomic characterization of non-small cell lung cancer in a comprehensive translational thoracic oncology database. ..." in: Journal of clinical bioinformatics, Vol. 1, Issue 8, pp. 1-11, (2011) (PubMed).

    Wang, Quah, Dong, Manser, Tang, Zeng: "PRL-3 down-regulates PTEN expression and signals through PI3K to promote epithelial-mesenchymal transition." in: Cancer research, Vol. 67, Issue 7, pp. 2922-6, (2007) (PubMed).

  • 抗原

    SNAIL (SNAI1)

    别名

    SNAI1

    背景

    The Drosophila embryonic protein snail is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo.
    Alias Symbols: SNA, SNAH, SNAIL, SLUGH2, SNAIL1, dJ710H13.1
    Protein Interaction Partner: MTUS2, KRT31, TRIM23, ACTN2, MID2, NOTCH2NL, KRTAP10-3, KRT40, FBXL5, EZH2, RNF2, RING1, LATS2, UBC, BTRC, TP53, MDM2, GSK3B, HDAC1, CHD4, KDM1A, HDAC3, HDAC2, RCOR1, FBXL14, NOTCH1, HIST1H3A, EGR1, AJUBA, Sin3a, HOXD4, SUZ12, CTDSP1, CTDSPL, CTDSP2, QRIC
    Protein Size: 264

    分子量

    29 kDa

    基因ID

    6615

    NCBI登录号

    NM_005985, NP_005976

    UniProt

    O95863

    途径

    Negative Regulation of intrinsic apoptotic Signaling
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