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SNAIL 抗体 (C-Term)

Name: SNAIL 抗体 (C-Term)
SKU: ABIN6265200
Availability: OutOfStock

SNAI1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

Western blot analysis of SNAI1 expression in HT29 whole cell lysates,The lane on the left is treated with the antigen-specific peptide. (SNAIL 抗体 (C-Term))

ABIN6269069 at 1/100 staining Mouse kidney tissue by IHC-P. (SNAIL 抗体 (C-Term))

IHC

ABIN6269069 staining HepG2? (SNAIL 抗体 (C-Term))

IF/ICC

5 images

(2 references)

产品编号 ABIN6265200

发货至: 中国

Datasheet as PDF

抗原 See all SNAIL (SNAI1) 抗体

SNAIL (SNAI1)
抗原表位
20

13

11

10

9

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1
C-Term
适用
89

33

18

6

3

3

3

1
人, 小鼠, 大鼠
宿主
79

10

3

2
兔
Compatible Secondaries
克隆类型
84

10
多克隆
标记
60

6

4

4

2

2

2

2

2

2

2

1

1

1

1

1

1
This SNAIL antibody is un-conjugated
应用范围
61

39

29

17

16

14

5

3

3

3

1

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

特异性

SNAIL Antibody detects endogenous levels of total SNAIL.

预测反应

Pig,Bovine,Horse,Rabbit,Dog,Chicken,Xenopus

纯化方法

The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

免疫原

A synthesized peptide derived from human SNAIL, corresponding to a region within C-terminal amino acids.

亚型

IgG

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anti-SNAIL (SNAI1) (C-Term) antibody
SNAI1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-SNAIL (SNAI1) (AA 1-100) antibody
SNAI1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-SNAIL (SNAI1) (N-Term) antibody
SNAI1 适用: 人, 小鼠, 大鼠, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-SNAIL (SNAI1) (AA 121-230) antibody
SNAI1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2G11 unconjugated

anti-SNAIL (SNAI1) (AA 1-264) antibody
SNAI1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-SNAIL (SNAI1) (AA 9-39), (N-Term) antibody
SNAI1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB01400 unconjugated

anti-SNAIL (SNAI1) antibody
SNAI1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-SNAIL (SNAI1) antibody
SNAI1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-SNAIL (SNAI1) (AA 9-39) antibody
SNAI1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-SNAIL (SNAI1) (pSer246) antibody
SNAI1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20 °C. Stable for 12 months from date of receipt.

有效期

12 months
Li, Xiao, Yang, Qin, Gao, Liu, Zhou: "Parthenolide attenuated bleomycin-induced pulmonary fibrosis via the NF-κB/Snail signaling pathway." in: Respiratory research, Vol. 19, Issue 1, pp. 111, (2018) (PubMed).

Li, Shen, Wang, Li, Wang, Jiang, Zhou, Feng: "EGCG regulates the cross-talk between JWA and topoisomerase IIα in non-small-cell lung cancer (NSCLC) cells." in: Scientific reports, Vol. 5, pp. 11009, (2016) (PubMed).
抗原

SNAIL (SNAI1)

别名

SNAI1 (SNAI1 产品)

别名

SLUGH2 antibody, SNA antibody, SNAH antibody, SNAIL antibody, SNAIL1 antibody, dJ710H13.1 antibody, AI194338 antibody, Sna antibody, Sna1 antibody, Snail antibody, Snail1 antibody, SNAI1 antibody, BG:DS01845.1 antibody, CG3956 antibody, Dmel\\CG3956 antibody, Sco antibody, br28 antibody, br29 antibody, l(2)35Db antibody, l(2)br28 antibody, l(2)br29 antibody, l(3)br28 antibody, l35Db antibody, sn antibody, Xsnail antibody, sna antibody, snail1 antibody, xSna antibody, Snai antibody, sna2 antibody, snail2 antibody, cb643 antibody, sna-1 antibody, sna1 antibody, snai1 antibody, snail1a antibody, zgc:109820 antibody, snail family transcriptional repressor 1 antibody, snail family zinc finger 1 antibody, snail homolog 1 (Drosophila) antibody, snail antibody, zinc-finger transcription factor Snail antibody, snail family zinc finger 1 S homeolog antibody, protein escargot antibody, transcription factor protein antibody, snail zinc finger protein antibody, snail family zinc finger 1b antibody, snail family zinc finger 1a antibody, SNAI1 antibody, Snai1 antibody, sna antibody, snail antibody, snai1.S antibody, LOC410464 antibody, snai1b antibody, snai1a antibody

背景

Description: Involved in induction of the epithelial to mesenchymal transition (EMT), formation and maintenance of embryonic mesoderm, growth arrest, survival and cell migration. Binds to 3 E-boxes of the E-cadherin/CDH1 gene promoter and to the promoters of CLDN7 and KRT8 and, in association with histone demethylase KDM1A which it recruits to the promoters, causes a decrease in dimethylated H3K4 levels and represses transcription. During EMT, involved with LOXL2 in negatively regulating pericentromeric heterochromatin transcription (By similarity). SNAI1 recruits LOXL2 to pericentromeric regions to oxidize histone H3 and repress transcription which leads to release of heterochromatin component CBX5/HP1A, enabling chromatin reorganization and acquisition of mesenchymal traits (By similarity). Associates with EGR1 and SP1 to mediate tetradecanoyl phorbol acetate (TPA)-induced up-regulation of CDKN2B, possibly by binding to the CDKN2B promoter region 5'-TCACA-3. In addition, may also activate the CDKN2B promoter by itself.
Gene: SNAI1

分子量

29kDa

基因ID

6615

UniProt

O95863

途径

Negative Regulation of intrinsic apoptotic Signaling