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Aprataxin 抗体 (N-Term)

The 兔 多克隆 anti-Aprataxin antibody (ABIN2777649) specifically detects Aprataxin in WB 和 IHC. The antibody is reactive with 人, 小鼠, 大鼠, 豚鼠, 犬, 马 和 兔 samples.
产品编号 ABIN2777649
发货至: 中国
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Quick Overview for Aprataxin 抗体 (N-Term) (ABIN2777649)

抗原

See all Aprataxin (APTX) 抗体
Aprataxin (APTX)

适用

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人, 小鼠, 大鼠, 豚鼠, 犬, 马, 兔

宿主

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克隆类型

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多克隆

标记

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This Aprataxin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    N-Term

    序列

    MMRVCWLVRQ DSRHQRIRLP HLEAVVIGRG PETKITDKKC SRQQVQLKAE

    预测反应

    Dog: 85%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

    产品特性

    This is a rabbit polyclonal antibody against APTX. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human APTX
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 342 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    Aprataxin (APTX)

    别名

    APTX

    背景

    APTX is a member of the histidine triad (HIT) superfamily, some of which have nucleotide-binding and diadenosine polyphosphate hydrolase activities. APTX may play a role in single-stranded DNA repair. Mutations in this gene have been associated with ataxia-ocular apraxia.This gene encodes a member of the histidine triad (HIT) superfamily, some of which have nucleotide-binding and diadenosine polyphosphate hydrolase activities. The encoded protein may play a role in single-stranded DNA repair. Mutations in this gene have been associated with ataxia-ocular apraxia. Multiple transcript variants encoding distinct isoforms have been identified for this gene, however, the full length nature of some variants has not been determined.
    Alias Symbols: AOA, AOA1, AXA1, EAOH, EOAHA, FHA-HIT
    Protein Interaction Partner: PNMA1, UBC, SUMO1, NEDD8, LIG3, HSPA4, XRCC1, DDX21, CNTROB, TSPYL2, CALCOCO1, SYT17, ZNF639, MAPKBP1, CEP350, PICK1, XRCC4, TRIM37, MBP, HIVEP1, BANF1, PARP1, TP53,
    Protein Size: 342

    分子量

    38 kDa

    基因ID

    54840

    NCBI登录号

    NM_175073, NP_778243

    UniProt

    Q6JV85

    途径

    DNA Damage Repair, Chromatin Binding
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