Aprataxin 抗体 (C-Term)
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北京 101111
Quick Overview for Aprataxin 抗体 (C-Term) (ABIN2778569)
抗原
See all Aprataxin (APTX) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- APTX Antibody - C-terminal region
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序列
- VIEMVQEAGR VTVRDGMPEL LKLPLRCHEC QQLLPSIPQL KEHLRKHWTQ
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预测反应
- Cow: 100%, Dog: 92%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against APTX. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human APTX
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anti-Aprataxin (APTX) (AA 93-342) antibody
APTX 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Aprataxin (APTX) (AA 69-166) antibodyAPTX 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 2H6 unconjugated
anti-Aprataxin (APTX) antibodyAPTX 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Aprataxin (APTX) (C-Term) antibodyAPTX 适用: 人, 小鼠, 大鼠, 豚鼠, Cow, 猴, Pig, Bat, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Aprataxin (APTX) antibodyAPTX 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB6830 unconjugated Recombinant Antibody
anti-Aprataxin (APTX) (AA 1-254) antibodyAPTX 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Aprataxin (APTX) antibodyAPTX 适用: 人, 小鼠, 大鼠 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Aprataxin (APTX) (AA 108-157) antibodyAPTX 适用: 人, 豚鼠, 犬, Cow, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Aprataxin (APTX) (N-Term) antibodyAPTX 适用: 人, 豚鼠, 犬, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Aprataxin (APTX) (AA 92-161) antibodyAPTX 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8094862
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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: "Aprataxin tumor levels predict response of colorectal cancer patients to irinotecan-based treatment." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 16, Issue 8, pp. 2375-82, (2010) (PubMed).
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- Aprataxin (APTX)
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别名
- APTX
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背景
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Background Information: APTX is a member of the histidine triad (HIT) superfamily, some of which have nucleotide-binding and diadenosine polyphosphate hydrolase activities. APTX may play a role in single-stranded DNA repair. Mutations in this gene have been associated with ataxia-ocular apraxia.This gene encodes a member of the histidine triad (HIT) superfamily, some of which have nucleotide-binding and diadenosine polyphosphate hydrolase activities. The encoded protein may play a role in single-stranded DNA repair. Mutations in this gene have been associated with ataxia-ocular apraxia. Multiple transcript variants encoding distinct isoforms have been identified for this gene, however, the full length nature of some variants has not been determined.This gene encodes a member of the histidine triad (HIT) superfamily, some of which have nucleotide-binding and diadenosine polyphosphate hydrolase activities. The encoded protein may play a role in single-stranded DNA repair. Mutations in this gene have been associated with ataxia-ocular apraxia. Multiple transcript variants encoding distinct isoforms have been identified for this gene, however, the full length nature of some variants has not been determined.
Gene Name: Aprataxin
Alternative Symbols: AOA, AOA1, AXA1, EAOH, EOAHA, FHA-HIT
Protein Name: Aprataxin
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分子量
- 38kDa
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基因ID
- 54840
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NCBI登录号
- NP_778243
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UniProt
- Q6JV85
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途径
- DNA Damage Repair, Chromatin Binding
抗原
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