Aprataxin 抗体 (Middle Region)
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北京 101111
Quick Overview for Aprataxin 抗体 (Middle Region) (ABIN2777648)
抗原
See all Aprataxin (APTX) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- YPYIVEFEEE AKNPGLETHR KRKRSGNSDS IERDAAQEAE AGTGLEPGSN
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预测反应
- Cow: 77%, Dog: 86%, Guinea Pig: 79%, Horse: 92%, Human: 100%, Rabbit: 86%
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产品特性
- This is a rabbit polyclonal antibody against APTX. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human APTX
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anti-Aprataxin (APTX) (AA 69-166) antibody
APTX 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 2H6 unconjugated
anti-Aprataxin (APTX) (AA 93-342) antibodyAPTX 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Aprataxin (APTX) antibodyAPTX 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Aprataxin (APTX) (AA 1-254) antibodyAPTX 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Aprataxin (APTX) (C-Term) antibodyAPTX 适用: 人, 小鼠, 大鼠, 豚鼠, Cow, 猴, Pig, Bat, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Aprataxin (APTX) antibodyAPTX 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB6830 unconjugated Recombinant Antibody
anti-Aprataxin (APTX) (C-Term) antibodyAPTX 适用: 人, 小鼠, 大鼠, 豚鼠, 犬, 马, 兔, Cow WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Aprataxin (APTX) antibodyAPTX 适用: 人, 小鼠, 大鼠 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Aprataxin (APTX) (N-Term) antibodyAPTX 适用: 人, 豚鼠, 犬, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Aprataxin (APTX) (AA 92-161) antibodyAPTX 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 306 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Aprataxin (APTX)
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别名
- APTX
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背景
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APTX is a member of the histidine triad (HIT) superfamily, some of which have nucleotide-binding and diadenosine polyphosphate hydrolase activities. The protein may play a role in single-stranded DNA repair. Mutations in this gene have been associated with ataxia-ocular apraxia. Multiple transcript variants encoding distinct isoforms have been identified for this gene, however, the full length nature of some variants has not been determined. This gene encodes a member of the histidine triad (HIT) superfamily, some of which have nucleotide-binding and diadenosine polyphosphate hydrolase activities. The encoded protein may play a role in single-stranded DNA repair. Mutations in this gene have been associated with ataxia-ocular apraxia. Multiple transcript variants encoding distinct isoforms have been identified for this gene, however, the full length nature of some variants has not been determined.
Alias Symbols: AOA, AOA1, AXA1, EAOH, EOAHA, FHA-HIT, FLJ20157, MGC1072
Protein Interaction Partner: PNMA1, UBC, SUMO1, NEDD8, LIG3, HSPA4, XRCC1, DDX21, CNTROB, TSPYL2, CALCOCO1, SYT17, ZNF639, MAPKBP1, CEP350, PICK1, XRCC4, TRIM37, MBP, HIVEP1, BANF1, PARP1, TP53,
Protein Size: 306 -
分子量
- 35 kDa
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基因ID
- 54840
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NCBI登录号
- NM_175069, NP_778239
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UniProt
- Q5T782
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途径
- DNA Damage Repair, Chromatin Binding
抗原
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