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PDK4 抗体 (N-Term)

This anti-PDK4 antibody is a 兔 多克隆 antibody detecting PDK4 in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, 马, Pig, 兔, Cow, 犬 和 豚鼠. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2777592
发货至: 中国

Quick Overview for PDK4 抗体 (N-Term) (ABIN2777592)

抗原

See all PDK4 抗体
PDK4 (Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4))

适用

人, 小鼠, 大鼠, 马, Pig, 兔, Cow, 犬, 豚鼠

宿主

  • 71
  • 13

克隆类型

  • 75
  • 11
多克隆

标记

  • 48
  • 7
  • 4
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This PDK4 antibody is un-conjugated

应用范围

  • 70
  • 41
  • 29
  • 13
  • 13
  • 9
  • 9
  • 8
  • 6
  • 3
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 15
    • 9
    • 8
    • 7
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    序列

    MKAARFVLRS AGSLNGAGLV PREVEHFSRY SPSPLSMKQL LDFGSENACE

    预测反应

    Cow: 92%, Dog: 92%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 92%, Pig: 100%, Rabbit: 100%, Rat: 92%

    产品特性

    This is a rabbit polyclonal antibody against PDK4. It was validated on Western Blot and immunohistochemistry.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human PDK4
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 411 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).

  • 抗原

    PDK4 (Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4))

    别名

    PDK4

    背景

    PDK4 is a member of the PDK/BCKDK protein kinase family and is a mitochondrial protein with a histidine kinase domain. This protein is located in the matrix of the mitrochondria and inhibits the pyruvate dehydrogenase complex by phosphorylating one of its subunits, thereby contributing to the regulation of glucose metabolism.This gene is a member of the PDK/BCKDK protein kinase family and encodes a mitochondrial protein with a histidine kinase domain. This protein is located in the matrix of the mitrochondria and inhibits the pyruvate dehydrogenase complex by phosphorylating one of its subunits, thereby contributing to the regulation of glucose metabolism. Expression of this gene is regulated by glucocorticoids, retinoic acid and insulin.
    Alias Symbols: FLJ40832
    Protein Interaction Partner: UBC, DLAT, PDK4, PDHA1, TRIM63,
    Protein Size: 411

    分子量

    46 kDa

    基因ID

    5166

    NCBI登录号

    NM_002612, NP_002603

    UniProt

    Q16654

    途径

    PI3K-Akt Signaling, Hedgehog Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect
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