HES1 抗体 (C-Term)
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- 抗原 See all HES1 抗体
- HES1 (Hes Family bHLH Transcription Factor 1 (HES1))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠, Cow, 兔, 豚鼠, Pig
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HES1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- AFLIPNGAFA HSGPVIPVYT SNSGTSVGPN AVSPSSGSSL TADSMWRPWR
- 预测反应
- Cow: 100%, Guinea Pig: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against Hes1. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide corresponding to a region of Rat
- Top Product
- Discover our top product HES1 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 281 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- HES1 (Hes Family bHLH Transcription Factor 1 (HES1))
- 别名
- Hes1 (HES1 产品)
- 别名
- HES-1 antibody, HHL antibody, HRY antibody, bHLHb39 antibody, Hry antibody, HAIRY1 antibody, c-hairy1A antibody, Xhairy1 antibody, hairy1 antibody, hes1 antibody, Xhairy-1 antibody, Xlh1 antibody, hes family bHLH transcription factor 1 antibody, hairy and enhancer of split 1 (Drosophila) antibody, hes family bHLH transcription factor 4 antibody, hes family bHLH transcription factor 1 S homeolog antibody, hes family bHLH transcription factor 1 L homeolog antibody, HES1 antibody, Hes1 antibody, HES4 antibody, hes1.S antibody, hes1.L antibody
- 背景
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Hes1 is the transcriptional repressor of genes that require a bHLH protein for their transcription. Hes1 may act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1. Hes1 binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity.
Alias Symbols: Hes1
Protein Interaction Partner: Polr2a, Kat2b, Sfpq, Src, Crebbp, Parp1, Camk2a,
Protein Size: 281 - 分子量
- 30 kDa
- 基因ID
- 29577
- NCBI登录号
- NM_024360, NP_077336
- UniProt
- Q04666
- 途径
- DNA Damage Repair
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