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HNF4A 抗体 (N-Term)

Name: HNF4A 抗体 (N-Term)
SKU: ABIN2777514
Availability: OutOfStock

Cited in 4+ publications. This 兔多克隆 anti-HNF4A antibody specifically detects HNF4A in WB. The antibody is reactive with 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠, 绵羊和斑马鱼 samples.

WB Suggested Anti-HNF4A Antibody Titration: 0. (HNF4A 抗体 (N-Term))

Host: Rabbit Target Name: HNF4A Sample Type: Human Fetal Heart Antibody Dilution: 1. (HNF4A 抗体 (N-Term))

Host: Rabbit Target Name: HNF4A Sample Tissue: Human Adult Placenta Antibody Dilution: 1. (HNF4A 抗体 (N-Term))

Host: Rabbit Target Name: HNF4A Sample Type: Human Fetal Lung Antibody Dilution: 1. (HNF4A 抗体 (N-Term))

WB Suggested Anti-HNF4A antibody Titration: 1 ug/mL Sample Type: Human Liver (HNF4A 抗体 (N-Term))

Host: Rat Target Name: HNF4A Sample Tissue: Rat Skeletal Muscle Antibody Dilution: 1ug/ml (HNF4A 抗体 (N-Term))

Host: Rabbit Target Name: HNF4A Sample Tissue: Human Lung Tumor Antibody Dilution: 1. (HNF4A 抗体 (N-Term))

8 images

(4 references)

产品编号 ABIN2777514

发货至: 中国

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Quick Overview for HNF4A 抗体 (N-Term) (ABIN2777514)

抗原

See all HNF4A 抗体

HNF4A (Hepatocyte Nuclear Factor 4, alpha (HNF4A))

适用

人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠, 绵羊, 斑马鱼

宿主

兔

克隆类型

多克隆

标记

This HNF4A antibody is un-conjugated

应用范围

Western Blotting (WB)

Discover our top product HNF4A Primary Antibody

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N-Term

序列

MRLSKTLVDM DMADYSAALD PAYTTLEFEN VQVLTMGNDT SPSEGTNLNA

预测反应

Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 93%

产品特性

This is a rabbit polyclonal antibody against HNF4A. It was validated on Western Blot.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the N-terminal region of Human HNF4A
anti-Hepatocyte Nuclear Factor 4, alpha (HNF4A) (AA 324-423) antibody
HNF4A 适用: 人 WB, ELISA, IF, RNAi 宿主: 小鼠 Monoclonal 4E2 unconjugated

anti-Hepatocyte Nuclear Factor 4, alpha (HNF4A) antibody
HNF4A 适用: 小鼠 WB, IHC, ChIP 宿主: 兔 Monoclonal unconjugated

anti-Hepatocyte Nuclear Factor 4, alpha (HNF4A) (pSer313) antibody
HNF4A 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Hepatocyte Nuclear Factor 4, alpha (HNF4A) (AA 1-464) antibody
HNF4A 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated

anti-Hepatocyte Nuclear Factor 4, alpha (HNF4A) (AA 281-312) antibody
HNF4A 适用: 人, 大鼠 WB, ELISA, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated

anti-Hepatocyte Nuclear Factor 4, alpha (HNF4A) (AA 200-300) antibody
HNF4A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Hepatocyte Nuclear Factor 4, alpha (HNF4A) (AA 1-464) antibody
HNF4A 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

anti-Hepatocyte Nuclear Factor 4, alpha (HNF4A) (N-Term) antibody
Verified HNF4A 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated

anti-Hepatocyte Nuclear Factor 4, alpha (HNF4A) (C-Term) antibody
HNF4A 适用: 人, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Hepatocyte Nuclear Factor 4, alpha (HNF4A) (Middle Region) antibody
HNF4A 适用: 人, 小鼠, 大鼠, Cow, Pig, 犬, 马, 兔, 豚鼠, 绵羊, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 474 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Faure, Schmidt, Watt, Schwalie, Wilson, Xu, Ramsay, Odom, Flicek: "Cohesin regulates tissue-specific expression by stabilizing highly occupied cis-regulatory modules." in: Genome research, Vol. 22, Issue 11, pp. 2163-75, (2012) (PubMed).

Schmidt, Wilson, Ballester, Schwalie, Brown, Marshall, Kutter, Watt, Martinez-Jimenez, Mackay, Talianidis, Flicek, Odom: "Five-vertebrate ChIP-seq reveals the evolutionary dynamics of transcription factor binding." in: Science (New York, N.Y.), Vol. 328, Issue 5981, pp. 1036-40, (2010) (PubMed).

Schmidt, Schwalie, Ross-Innes, Hurtado, Brown, Carroll, Flicek, Odom: "A CTCF-independent role for cohesin in tissue-specific transcription." in: Genome research, Vol. 20, Issue 5, pp. 578-88, (2010) (PubMed).

Weedon, Owen, Shields, Hitman, Walker, McCarthy, Love-Gregory, Permutt, Hattersley, Frayling: "Common variants of the hepatocyte nuclear factor-4alpha P2 promoter are associated with type 2 diabetes in the U.K. population." in: Diabetes, Vol. 53, Issue 11, pp. 3002-6, (2004) (PubMed).
抗原

HNF4A (Hepatocyte Nuclear Factor 4, alpha (HNF4A))

别名

HNF4A

背景

The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms.
Alias Symbols: HNF4, HNF4a7, HNF4a8, HNF4a9, HNF4alpha, MODY, MODY1, NR2A1, NR2A21, TCF, TCF14
Protein Interaction Partner: PIAS4, SUMO1, SUMO2, RNF4, SUB1, CREBBP, TBP, TAF9, TAF6, TADA2A, GTF2H1, GTF2B, ANP32B, MDM2, GPS2, PPARGC1A, HNF4A, NCOA6, SMAD4, SMAD3, PNRC2, COPS5, PNRC1, NR0B2, NRIP1, UBE2I, PROX1, NPPA, SREBF2, VDR, MAPK3, MAPK1, SIRT1, SREBF1, XPO1, SP1, HDAC3, T
Protein Size: 474

分子量

53 kDa

基因ID

3172

NCBI登录号

NM_000457, NP_000448

UniProt

P41235

途径

AMPK Signaling, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, Cell-Cell Junction Organization, Regulation of Carbohydrate Metabolic Process