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HMGB2 抗体 (C-Term)

This anti-HMGB2 antibody is a 兔 多克隆 antibody detecting HMGB2 in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠 和 斑马鱼.
产品编号 ABIN2777510
发货至: 中国

Quick Overview for HMGB2 抗体 (C-Term) (ABIN2777510)

抗原

See all HMGB2 抗体
HMGB2 (High Mobility Group Box 2 (HMGB2))

适用

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人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠, 斑马鱼

宿主

  • 42
  • 11

克隆类型

  • 39
  • 14
多克隆

标记

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This HMGB2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    C-Term

    序列

    AAYRAKGKSE AGKKGPGRPT GSKKKNEPED EEEEEEEEDE DEEEEDEDEE

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

    产品特性

    This is a rabbit polyclonal antibody against HMGB2. It was validated on Western Blot and immunohistochemistry.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human HMGB2
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 209 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    HMGB2 (High Mobility Group Box 2 (HMGB2))

    别名

    HMGB2

    背景

    This protein is a member of the non-histone chromosomal high mobility group family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in the DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.This gene encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: HMG2
    Protein Interaction Partner: PKNOX1, UBC, EED, YWHAG, PGD, LDHB, CKB, HMGA1, GZMK, GZMA, CSNK1A1, FN1, SCAF8, APP, TFAP4, CDK2, BKRF1, Cebpb, ELAVL1, HMGB1, CHAF1A, CREBBP, SET, PGR, POU3F1, PRKDC, TP53, RAG1, POU5F1, POU2F2, POU2F1, APEX1, AR, NR3C1,
    Protein Size: 209

    分子量

    24 kDa

    基因ID

    3148

    NCBI登录号

    NM_002129, NP_002120

    UniProt

    P26583

    途径

    Cellular Response to Molecule of Bacterial Origin
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