POU1F1 抗体 (C-Term)
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北京 101111
Quick Overview for POU1F1 抗体 (C-Term) (ABIN182359)
抗原
See all POU1F1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- POU1F1 Antibody - C-terminal region
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序列
- QEIMRMAEEL NLEKEVVRVW FCNRRQREKR VKTSLNQSLF SISKEHLECR
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预测反应
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 86%
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产品特性
- This is a rabbit polyclonal antibody against POU1F1. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human POU1F1
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8108742
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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: "HIF prolyl hydroxylase-3 mediates alpha-ketoglutarate-induced apoptosis and tumor suppression." in: Journal of molecular medicine (Berlin, Germany), Vol. 88, Issue 8, pp. 839-49, (2010) (PubMed).
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- POU1F1 (POU Class 1 Homeobox 1 (POU1F1))
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别名
- POU1F1
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背景
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Background Information: PIT1 is a pituitary-specific transcription factor responsible for pituitary development and hormone expression in mammals and is a member of the POU family of transcription factors that regulate mammalian development. The POU family is so named because the first 3 members identified were PIT1 and OCT1 of mammals, and Unc-86 of C. elegans. PIT1 contains 2 protein domains, termed POU-specific and POU-homeo, which are both necessary for high affinity DNA binding on genes encoding growth hormone and prolactin. PIT1 is also important for regulation of the genes encoding prolactin and thyroid-stimulating hormone beta subunit by thyrotropin-releasing hormone and cyclic AMP.
Gene Name: POU class 1 homeobox 1
Alternative Symbols: PIT1, CPHD1, GHF-1, Pit-1, POU1F1a
Protein Name: Pituitary-specific positive transcription factor 1
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分子量
- 33kDa
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基因ID
- 5449
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NCBI登录号
- NP_000297
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UniProt
- P28069
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途径
- Regulation of Carbohydrate Metabolic Process
抗原
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