POU1F1 抗体 (full length)
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北京 101111
Quick Overview for POU1F1 抗体 (full length) (ABIN7878832)
抗原
See all POU1F1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- full length
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原理
- POU1F1 Antibody / PIT-1 / GHF-1
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纯化方法
- Protein A/G affinity
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免疫原
- Recombinant human full-length protein was used as the immunogen for the POU1F1 antibody.
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亚型
- IgG2b, kappa
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anti-POU Class 1 Homeobox 1 (POU1F1) (C-Term) antibody
POU1F1 适用: 人, 小鼠, 大鼠, 犬, Cow, 山羊, 马, 兔, 绵羊, 豚鼠, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-POU Class 1 Homeobox 1 (POU1F1) (AA 75-124) antibodyPOU1F1 适用: 人, 小鼠, 大鼠, 犬, Cow, 山羊, 马, 兔, 绵羊, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-POU Class 1 Homeobox 1 (POU1F1) antibodyPOU1F1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-POU Class 1 Homeobox 1 (POU1F1) (C-Term) antibodyPOU1F1 适用: 人, 小鼠, 大鼠, 犬, Cow, 山羊, 马, 兔, 绵羊, 豚鼠, Pig, 斑马鱼, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-POU Class 1 Homeobox 1 (POU1F1) (N-Term) antibodyPOU1F1 适用: 人, 小鼠, 大鼠, 犬, Cow, 山羊, 马, 兔, 绵羊, 豚鼠, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-POU Class 1 Homeobox 1 (POU1F1) (N-Term) antibodyPOU1F1 适用: 人, 小鼠, 大鼠, 犬, Cow, Pig, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-POU Class 1 Homeobox 1 (POU1F1) antibodyPOU1F1 适用: 人, 犬 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the POU1F1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the POU1F1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- POU1F1 (POU Class 1 Homeobox 1 (POU1F1))
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别名
- POU1F1
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背景
- Transcriptional regulators play a critical role in development by mediating tissue- and cell-specific transcription. POU domain factors are transcriptional regulators characterized by a bipartite DNA binding domain, which consists of two highly conserved regions, tethered by a variable linker of 14-26 amino acids. Pit-1, also known as growth hormone factor-1 (GHF-1), a member of the POU homeodomain family, is essential for the normal development of the anterior pituitary gland, where it is required for the formation of somatotropes, lactotropes and thyrotropes. In somatotropes and lactotropes, Pit-1 activates the production of growth hormone and Prolactin, respectively. In addition, Pit-1 acts as a repressor of gene expression, which allows for the differentiation of specific cell types. Pit-1 is expressed as two alternatively spliced products, designated Pit-1a and Pit-1b, which differ in their trans-activation ability. Mutations in the Pit-1 gene are believed to result in combined pituitary hormone deficiency (CPHD) for growth hormone, Prolactin and thyroid stimulating hormone. The gene which encodes Pit-1 maps to human chromosome 3p11.2.
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UniProt
- P28069
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途径
- Regulation of Carbohydrate Metabolic Process
抗原
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