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BDNF 抗体 (Middle Region)

Name: BDNF 抗体 (Middle Region)
SKU: ABIN2777093
Availability: OutOfStock

This anti-BDNF antibody is a 兔多克隆 antibody detecting BDNF in WB 和 IHC. Suitable for 人, 大鼠, 小鼠, Pig, 兔, 马和犬. This Primary Antibody has been cited in 6+ publications.

WB Suggested Anti-BDNF Antibody Titration: 0. (BDNF 抗体 (Middle Region))

Immunohistochemistry (IHC) image for anti-Brain-Derived Neurotrophic Factor (BDNF) (Middle Region) antibody (ABIN2777093) (BDNF 抗体 (Middle Region))

IHC

Sample Type : Rhesus macaque spinal cord Primary Antibody Dilution : 1:300 Secondary Antibody : Donkey anti Rabbit 488 Secondary Antibody Dilution : 1:500 Color/Signal Descriptions : Green: BDNF Gene Name : BDNF Submitted by : Timur Mavlyutov, Ph. (BDNF 抗体 (Middle Region))

IHC

Host: Rabbit Target Name: BDNF Sample Tissue: Human ACHN Antibody Dilution: 1. (BDNF 抗体 (Middle Region))

Host: Mouse Target Name: BDNF Sample Tissue: Mouse Testis Antibody Dilution: 1ug/ml (BDNF 抗体 (Middle Region))

Host: Rabbit Target Name: BDNF Sample Type: ACHN Whole Cell lysates Antibody Dilution: 1ug/ml (BDNF 抗体 (Middle Region))

Host: Rabbit Target Name: BDNF Sample Tissue: Human Ovary Tumor Antibody Dilution: 1ug/ml (BDNF 抗体 (Middle Region))

Host: Mouse Target Name: BDNF Sample Tissue: Mouse Brain Antibody Dilution: 1ug/ml (BDNF 抗体 (Middle Region))

Host: Mouse Target Name: BDNF Sample Tissue: Mouse Pancreas Antibody Dilution: 1ug/ml (BDNF 抗体 (Middle Region))

Host: Rabbit Target Name: BDNF Sample Type: Fetal Liver lysates Antibody Dilution: 0. (BDNF 抗体 (Middle Region))

10 images

(6 references)

产品编号 ABIN2777093

发货至: 中国

Quick Overview for BDNF 抗体 (Middle Region) (ABIN2777093)

抗原

See all BDNF 抗体

BDNF (Brain-Derived Neurotrophic Factor (BDNF))

适用

人, 大鼠, 小鼠, Pig, 兔, 马, 犬

宿主

兔

克隆类型

多克隆

标记

This BDNF antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC)

Discover our top product BDNF Primary Antibody

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Middle Region

序列

EWVTAADKKT AVDMSGGTVT VLEKVPVSKG QLKQYFYETK CNPMGYTKEG

预测反应

Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

产品特性

This is a rabbit polyclonal antibody against BDNF. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the middle region of human BDNF
anti-Brain-Derived Neurotrophic Factor (BDNF) (AA 20-252) antibody
BDNF 适用: Pig WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Brain-Derived Neurotrophic Factor (BDNF) (AA 19-248) antibody
BDNF 适用: 人 WB, ELISA, ICC 宿主: 小鼠 Monoclonal 3D9C5 unconjugated

anti-Brain-Derived Neurotrophic Factor (BDNF) (AA 151-247) antibody
BDNF 适用: 人, 大鼠, 小鼠 WB, ELISA, ICC, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Brain-Derived Neurotrophic Factor (BDNF) (AA 20-252) antibody
BDNF 适用: Pig WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C2 unconjugated

anti-Brain-Derived Neurotrophic Factor (BDNF) (Internal Region) antibody
Verified BDNF 适用: 人 ELISA, IF 宿主: 山羊 Polyclonal unconjugated

anti-Brain-Derived Neurotrophic Factor (BDNF) (AA 1-247) antibody
BDNF 适用: 人 WB, ELISA, IP, IF 宿主: 小鼠 Monoclonal 1B10 unconjugated

anti-Brain-Derived Neurotrophic Factor (BDNF) (AA 129-247) antibody
BDNF 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Brain-Derived Neurotrophic Factor (BDNF) (AA 206-236) antibody
BDNF 适用: 人 WB, IHC, ELISA, IF, FACS 宿主: 兔 Polyclonal unconjugated

anti-Brain-Derived Neurotrophic Factor (BDNF) (AA 129-247) antibody
BDNF 适用: 人, 大鼠, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Brain-Derived Neurotrophic Factor (BDNF) (AA 20-247) antibody
BDNF 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 247 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
McCarthy, Mueller, Cannon, Huizenga, Darnell, Bhide, Sadri-Vakili: "Prenatal Cocaine Exposure Alters BDNF-TrkB Signaling in the Embryonic and Adult Brain." in: Developmental neuroscience, Vol. 38, Issue 5, pp. 365-374, (2017) (PubMed).

McCarthy, Bell, Cannon, Mueller, Huizenga, Sadri-Vakili, Fadool, Bhide: "Reversal Learning Deficits Associated with Increased Frontal Cortical Brain-Derived Neurotrophic Factor Tyrosine Kinase B Signaling in a Prenatal Cocaine Exposure Mouse Model." in: Developmental neuroscience, Vol. 38, Issue 5, pp. 354-364, (2016) (PubMed).

Kight, McCarthy: "Sex differences and estrogen regulation of BDNF gene expression, but not propeptide content, in the developing hippocampus." in: Journal of neuroscience research, Vol. 95, Issue 1-2, pp. 345-354, (2016) (PubMed).

Kasemeier-Kulesa, Morrison, Lefcort, Kulesa: "TrkB/BDNF signalling patterns the sympathetic nervous system." in: Nature communications, Vol. 6, pp. 8281, (2015) (PubMed).

Vassoler, White, Schmidt, Sadri-Vakili, Pierce: "Epigenetic inheritance of a cocaine-resistance phenotype." in: Nature neuroscience, Vol. 16, Issue 1, pp. 42-7, (2012) (PubMed).

McCarthy, Zhang, Darnell, Sangrey, Yanagawa, Sadri-Vakili, Bhide: "Cocaine alters BDNF expression and neuronal migration in the embryonic mouse forebrain." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 31, Issue 38, pp. 13400-11, (2011) (PubMed).
抗原

BDNF (Brain-Derived Neurotrophic Factor (BDNF))

别名

BDNF

背景

BDNF is a member of the nerve growth factor family. It is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression BDNF is reduced in both Alzheimer's and Huntington disease patients. BDNF may play a role in the regulation of stress response and in the biology of mood disorders.The protein encoded by this gene is a member of the nerve growth factor family. It is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of this gene is reduced in both Alzheimer's and Huntington disease patients. This gene may play a role in the regulation of stress response and in the biology of mood disorders. Multiple transcript variants encoding distinct isoforms have been described for this gene, but the full-length nature of only some could be determined.
Alias Symbols: MGC34632
Protein Interaction Partner: UBC, AGO3, INPP5K, F11R, JUNB, APP, ELAVL1, Ntrk2, CADPS2, MBTPS1, SORT1, NOS3, NTF4, NTF3, ESR1, NCAM1, CPE, BDNF,
Protein Size: 247

分子量

27 kDa

基因ID

627

NCBI登录号

NM_001709, NP_001700

UniProt

P23560

途径

RTK signaling, Synaptic Membrane, Feeding Behaviour, Dicarboxylic Acid Transport, Regulation of long-term Neuronal Synaptic Plasticity