Prostate Specific Antigen 抗体 (Middle Region)
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北京 101111
Quick Overview for Prostate Specific Antigen 抗体 (Middle Region) (ABIN2777044)
抗原
See all Prostate Specific Antigen (PSA) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- KLK3 Antibody - middle region
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序列
- LRPGDDSSHD LMLLRLSEPA ELTDAVKVMD LPTQEPALGT TCYASGWGSI
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预测反应
- Dog: 77%, Human: 100%, Mouse: 86%, Rat: 86%
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产品特性
- This is a rabbit polyclonal antibody against KLK3. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP41879-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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: "Measurement of serum prostate cancer markers using a nanopore thin film based optofluidic chip." in: Biosensors & bioelectronics, Vol. 77, pp. 491-8, (2015) (PubMed).
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- Prostate Specific Antigen (PSA)
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别名
- KLK3
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背景
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Background Information: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms.
Gene Name: Kallikrein-related peptidase 3
Alternative Symbols: APS, PSA, hK3, KLK2A1
Protein Name: Prostate-specific antigen
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分子量
- 26kDa
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基因ID
- 354
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NCBI登录号
- NP_001639
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UniProt
- P07288
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途径
- Complement System
抗原
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