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MUC1 抗体 (N-Term)

Name: MUC1 抗体 (N-Term)
SKU: ABIN2776851
Availability: OutOfStock

MUC1 适用: 人, Cow, 犬, Pig, 兔, 山羊 IHC, WB 宿主: 兔 Polyclonal unconjugated

Immunohistochemistry (IHC) image for anti-Mucin 1 (MUC1) (N-Term) antibody (ABIN2776851) (MUC1 抗体 (N-Term))

IHC

Western Blotting (WB) image for anti-Mucin 1 (MUC1) (N-Term) antibody (ABIN2776851) (MUC1 抗体 (N-Term))

Host: Rabbit Target Name: MUC1 Sample Type: 721_B Antibody Dilution: 1. (MUC1 抗体 (N-Term))

3 images

产品编号 ABIN2776851

发货至: 中国

Datasheet as PDF

抗原 See all MUC1 抗体

MUC1 (Mucin 1 (MUC1))
抗原表位
21

16

16

14

7

5

5

5

4

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
N-Term
适用
254

59

32

11

5

5

3

3

2

2

2

2

1
人, Cow, 犬, Pig, 兔, 山羊
宿主
168

97

2

1

1
兔
Compatible Secondaries
克隆类型
147

115

7
多克隆
标记
156

20

13

7

7

6

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1
This MUC1 antibody is un-conjugated
应用范围
135

127

103

92

73

47

25

24

20

19

16

14

13

13

6

6

6

4

4

3

2

2

2

2

2

2

2

1

1

1

1
Immunohistochemistry (IHC), Western Blotting (WB)

序列

SATQRSSVPS STEKNALSTG VSFFFLSFHI SNLQFNSSLE DPSTDYYQEL

预测反应

Cow: 86%, Dog: 86%, Goat: 86%, Human: 100%, Pig: 82%, Rabbit: 86%

产品特性

This is a rabbit polyclonal antibody against MUC1. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the N terminal region of human MUC1

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应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 273 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
抗原

MUC1 (Mucin 1 (MUC1))

别名

MUC1 (MUC1 产品)

背景

MUC1 is a membrane bound, glycosylated phosphoprotein. The protein is anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. It also includes a 20 aa variable number tandem repeat (VNTR) domain, with the number of repeats varying from 20 to 120 in different individuals. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas.This gene is a member of the mucin family and encodes a membrane bound, glycosylated phosphoprotein. The protein is anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. It also includes a 20 aa variable number tandem repeat (VNTR) domain, with the number of repeats varying from 20 to 120 in different individuals. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length nature of only some has been determined.
Alias Symbols: CD227, EMA, H23AG, MAM6, PEM, PEMT, PUM, KL-6, MUC-1, MUC-1/X, MUC1/ZD, MUC-1/SEC
Protein Interaction Partner: UBC, PPARG, IPO5, NUP62, EGFR, ABL1, SRC, JUN, TP53, TBP, IKBKG, TNFRSF1A, IKBKB, GRB2, ESR1, GALNT15, GALNT12, GALNT10, OSGEP, GSK3B, GALNT2, GALNT1, CTNND1, SIGLEC1, ERBB4, ERBB3, SOS1, PRKCD, ZAP70, APC, JUP, LYN, ERBB2, LCK, CTNNB1, GALNT4, BAX, CDKN1
Protein Size: 273

分子量

27 kDa

基因ID

4582

NCBI登录号

NM_002456, NP_002447

UniProt

P15941

途径

Negative Regulation of intrinsic apoptotic Signaling