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MUC1 抗体 (C-Term)

This anti-MUC1 antibody is a 兔 多克隆 antibody detecting MUC1 in IHC 和 WB. Suitable for 人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠 和 马.
产品编号 ABIN2776819
发货至: 中国
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Quick Overview for MUC1 抗体 (C-Term) (ABIN2776819)

抗原

See all MUC1 抗体
MUC1 (Mucin 1 (MUC1))

适用

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人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠, 马

宿主

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克隆类型

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多克隆

标记

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This MUC1 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Western Blotting (WB)
  • 抗原表位

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    C-Term

    序列

    GQLDIFPARD TYHPMSEYPT YHTHGRYVPP SSTDRSPYEK VSAGNGGSSL

    预测反应

    Cow: 92%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against MUC1. It was validated on Western Blot and immunohistochemistry.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human MUC1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 203 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    MUC1 (Mucin 1 (MUC1))

    别名

    MUC1

    背景

    MUC1 is a membrane bound, glycosylated phosphoprotein. The protein is anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. It also includes a 20 aa variable number tandem repeat (VNTR) domain, with the number of repeats varying from 20 to 120 in different individuals. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas.
    Alias Symbols: CD227, EMA, PEM, PUM, mucin, KL-6, MAM6, PEMT, H23AG, MUC-1, MUC-1/X, MUC1/ZD, MUC-1/SEC
    Protein Interaction Partner: UBC, PPARG, IPO5, NUP62, EGFR, ABL1, SRC, JUN, TP53, TBP, IKBKG, TNFRSF1A, IKBKB, GRB2, ESR1, GALNT15, GALNT12, GALNT10, OSGEP, GSK3B, GALNT2, GALNT1, CTNND1, SIGLEC1, ERBB4, ERBB3, SOS1, PRKCD, ZAP70, APC, JUP, LYN, ERBB2, LCK, CTNNB1, GALNT4, BAX, CDKN1
    Protein Size: 203

    分子量

    22 kDa

    基因ID

    4582

    NCBI登录号

    NM_001044390, NP_001037855

    UniProt

    Q7Z552

    途径

    Negative Regulation of intrinsic apoptotic Signaling
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