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MUC1 抗体 (Middle Region)

Name: MUC1 抗体 (Middle Region)
SKU: ABIN2776818
Availability: OutOfStock

This anti-MUC1 antibody is a 兔多克隆 antibody detecting MUC1 in IHC 和 WB. Suitable for 人, 小鼠, 大鼠, Cow, 犬, Pig, 兔和山羊.

Sample Type : Human stomach Primary Antibody Dilution : 1:200 Secondary Antibody : Anti-rabbit-HRP Secondary Antibody Dilution : 1:1000 Color/Signal Descriptions : Brown: MUC1 Blue: Nucleus Gene Name : MUC1 Submitted by : Dr. (MUC1 抗体 (Middle Region))

IHC

WB Suggested Anti-MUC1 Antibody Titration: 0. (MUC1 抗体 (Middle Region))

Sample Type : Pig stomach Primary Antibody Dilution : 1:200 Secondary Antibody : Anti-rabbit-HRP Secondary Antibody Dilution : 1:1000 Color/Signal Descriptions : Brown: MUC1 Blue: Nucleus Gene Name : MUC1 Submitted by : Dr. (MUC1 抗体 (Middle Region))

IHC

3 images

产品编号 ABIN2776818

发货至: 中国

Datasheet as PDF

Quick Overview for MUC1 抗体 (Middle Region) (ABIN2776818)

抗原

See all MUC1 抗体

MUC1 (Mucin 1 (MUC1))

适用

人, 小鼠, 大鼠, Cow, 犬, Pig, 兔, 山羊

宿主

兔

克隆类型

多克隆

标记

This MUC1 antibody is un-conjugated

应用范围

Immunohistochemistry (IHC), Western Blotting (WB)

Discover our top product MUC1 Primary Antibody

抗原表位
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Middle Region

序列

ASSTPGGEKE TSATQRSSVP SSTEKNAFNS SLEDPSTDYY QELQRDISEM

预测反应

Cow: 79%, Dog: 79%, Goat: 79%, Human: 100%, Mouse: 86%, Pig: 83%, Rabbit: 86%, Rat: 93%

产品特性

This is a rabbit polyclonal antibody against MUC1. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the middle region of human MUC1
anti-Mucin 1 (MUC1) (AA 474-630) antibody
MUC1 适用: 小鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Mucin 1 (MUC1) (AA 410-525) antibody
MUC1 适用: 小鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Mucin 1 (MUC1) antibody
MUC1 适用: 人, 小鼠 IHC, WB, ELISA, FACS, IF, Coat, StM 宿主: 小鼠 Monoclonal MUC1-955 unconjugated

anti-Mucin 1 (MUC1) antibody
MUC1 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal MUC1-520 unconjugated

anti-Mucin 1 (MUC1) antibody
MUC1 适用: 人 IHC, WB, IHC (p) 宿主: 小鼠 Monoclonal 2E3 unconjugated

anti-Mucin 1 (MUC1) (AA 1182-1255) antibody
MUC1 适用: 人 IHC, WB 宿主: 兔 Polyclonal unconjugated

anti-Mucin 1 (MUC1) (AA 66-175) antibody
MUC1 适用: 人 IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 3B10B4 unconjugated

anti-Mucin 1 (MUC1) (AA 1098-1255) antibody
MUC1 适用: 人 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Mucin 1 (MUC1) (AA 404-655) antibody
MUC1 适用: 大鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Mucin 1 (MUC1) (AA 1062-1139) antibody
MUC1 适用: 人, 小鼠, 大鼠 IHC, WB, ELISA 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 159 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
抗原

MUC1 (Mucin 1 (MUC1))

别名

MUC1

背景

MUC1 is a membrane bound, glycosylated phosphoprotein. The protein is anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. It also includes a 20 aa variable number tandem repeat (VNTR) domain, with the number of repeats varying from 20 to 120 in different individuals. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is a member of the mucin family and encodes a membrane bound, glycosylated phosphoprotein. The protein is anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. It also includes a 20 aa variable number tandem repeat (VNTR) domain, with the number of repeats varying from 20 to 120 in different individuals. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length nature of only some has been determined.
Alias Symbols: CD227, EMA, H23AG, MAM6, PEM, PEMT, PUM, KL-6, MUC-1, MUC-1/X, MUC1/ZD, MUC-1/SEC
Protein Interaction Partner: UBC, PPARG, IPO5, NUP62, EGFR, ABL1, SRC, JUN, TP53, TBP, IKBKG, TNFRSF1A, IKBKB, GRB2, ESR1, GALNT15, GALNT12, GALNT10, OSGEP, GSK3B, GALNT2, GALNT1, CTNND1, SIGLEC1, ERBB4, ERBB3, SOS1, PRKCD, ZAP70, APC, JUP, LYN, ERBB2, LCK, CTNNB1, GALNT4, BAX, CDKN1
Protein Size: 159

分子量

14 kDa

基因ID

4582

NCBI登录号

NM_001044392, NP_001037857

UniProt

Q7Z550

途径

Negative Regulation of intrinsic apoptotic Signaling