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Insulin Receptor 抗体 (Middle Region)

This 兔 多克隆 antibody specifically detects Insulin Receptor in WB 和 IHC. It exhibits reactivity toward 人, 小鼠, 大鼠, 犬, 马, Cow, 豚鼠, 兔 和 Pig.
产品编号 ABIN2776774
发货至: 中国
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Quick Overview for Insulin Receptor 抗体 (Middle Region) (ABIN2776774)

抗原

See all Insulin Receptor (INSR) 抗体
Insulin Receptor (INSR)

适用

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人, 小鼠, 大鼠, 犬, 马, Cow, 豚鼠, 兔, Pig

宿主

  • 177
  • 39
  • 6
  • 2
  • 1

克隆类型

  • 145
  • 80
多克隆

标记

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This Insulin Receptor antibody is un-conjugated

应用范围

  • 156
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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 16
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    • 11
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    • 5
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    Middle Region

    序列

    ENNVVHLMWQ EPKEPNGLIV LYEVSYRRYG DEELHLCVSR KHFALERGCR

    预测反应

    Cow: 93%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against INSR. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human INSR
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 1382 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    Insulin Receptor (INSR)

    别名

    INSR

    背景

    This receptor binds insulin and has a tyrosine-protein kinase activity. Isoform Short has a higher affinity for insulin. INSR mediates the metabolic functions of insulin. INSR binding to insulin stimulates association of the receptor with downstream media
    Alias Symbols: CD220, HHF5
    Protein Interaction Partner: KRT31, UBC, ARRB2, MOK, Grb2, Hgf, DOK1, SH2B1, Stat5b, TEAD1, STAT5A, JAK2, JAK1, IRS1, IRF7, PLCG1, GRB10, Socs6, Socs1, SOCS3, SH2B2, HGS, INPPL1, Calmodulin, Mad2l1, KRT27, DOK5, DOK4, SNX6, SNX4, SNX2, ACP1, PTPN2, SYNCRIP, FRS2, PIK3R3, VAV3, ARHGAP
    Protein Size: 1382

    分子量

    154 kDa

    基因ID

    3643

    NCBI登录号

    NM_000208, NP_000199

    UniProt

    P06213

    途径

    NF-kappaB Signaling, RTK signaling, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity
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