Insulin Receptor 抗体 (Middle Region)
Quick Overview for Insulin Receptor 抗体 (Middle Region) (ABIN2776773)
抗原
See all Insulin Receptor (INSR) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- EEVSGTKGRQ ERNDIALKTN GDQASCENEL LKFSFIRTSF DKILLRWEPY
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%
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产品特性
- This is a rabbit polyclonal antibody against Insr. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide corresponding to a region of Mouse
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 1372 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Insulin Receptor (INSR)
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别名
- Insr
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背景
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This receptor binds insulin and has a tyrosine-protein kinase activity. When it is present in a hybrid receptor with IGF1R, binds IGF1.
Alias Symbols: 4932439J01Rik, CD220, D630014A15Rik, IR, IR-A, IR-B
Protein Interaction Partner: Arrb2, Src, Akt1, Jup, Irs1, Grb10, Snx9, Dok3, Sh2b2, Flot1, Dok1, Cav3, Socs1, Socs3, Sorbs1, Cav1, Pik3r1,
Protein Size: 1372 -
分子量
- 155 kDa
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基因ID
- 16337
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NCBI登录号
- NM_010568, NP_034698
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UniProt
- P15208
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途径
- NF-kappaB Signaling, RTK signaling, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity
抗原
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