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MSH2 抗体 (N-Term)

This anti-MSH2 antibody is a 兔 多克隆 antibody detecting MSH2 in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, 犬, 豚鼠, 斑马鱼, Cow, 马 和 兔. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2776761
发货至: 中国

Quick Overview for MSH2 抗体 (N-Term) (ABIN2776761)

抗原

See all MSH2 抗体
MSH2 (Mismatch Repair Protein 2 (MSH2))

适用

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人, 小鼠, 大鼠, 犬, 豚鼠, 斑马鱼, Cow, 马, 兔

宿主

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克隆类型

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多克隆

标记

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This MSH2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    N-Term

    序列

    GNKASKENDW YLAYKASPGN LSQFEDILFG NNDMSASIGV VGVKMSAVDG

    预测反应

    Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%, Zebrafish: 79%

    产品特性

    This is a rabbit polyclonal antibody against MSH2. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human MSH2
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 934 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Wedrén, Lovmar, Humphreys, Magnusson, Melhus, Syvänen, Kindmark, Landegren, Fermér, Stiger, Persson, Baron, Weiderpass: "Estrogen receptor alpha gene polymorphism and endometrial cancer risk--a case-control study." in: BMC cancer, Vol. 8, pp. 322, (2009) (PubMed).

  • 抗原

    MSH2 (Mismatch Repair Protein 2 (MSH2))

    别名

    MSH2

    背景

    MSH2 was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. MSH2 was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: COCA1, FCC1, HNPCC, HNPCC1, LCFS2
    Protein Interaction Partner: ESR1, BRCA1, SUMO2, RPA3, RPA2, RPA1, REV1, POLK, DPYSL3, ATP6V1B2, CUL2, XRCC5, SUPT5H, STAT3, ST13, PDE3A, NRD1, JUP, XRCC6, SEC23A, HDAC6, PCNA, MSH3, MSH6, ERCC4, ERCC1, gag-pol, UBC, SUPT16H, SEPT9, SRSF10, SRSF11, SART1, SMARCA5, TOP2B, SRSF7, SRSF5
    Protein Size: 934

    分子量

    105 kDa

    基因ID

    4436

    NCBI登录号

    NM_000251, NP_000242

    UniProt

    P43246

    途径

    DNA Damage Repair, Production of Molecular Mediator of Immune Response
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