MSH2 抗体 (N-Term)
Quick Overview for MSH2 抗体 (N-Term) (ABIN2776761)
抗原
See all MSH2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- GNKASKENDW YLAYKASPGN LSQFEDILFG NNDMSASIGV VGVKMSAVDG
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预测反应
- Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%, Zebrafish: 79%
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产品特性
- This is a rabbit polyclonal antibody against MSH2. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human MSH2
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 934 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Estrogen receptor alpha gene polymorphism and endometrial cancer risk--a case-control study." in: BMC cancer, Vol. 8, pp. 322, (2009) (PubMed).
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Estrogen receptor alpha gene polymorphism and endometrial cancer risk--a case-control study." in: BMC cancer, Vol. 8, pp. 322, (2009) (PubMed).
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- MSH2 (Mismatch Repair Protein 2 (MSH2))
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别名
- MSH2
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背景
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MSH2 was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. MSH2 was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: COCA1, FCC1, HNPCC, HNPCC1, LCFS2
Protein Interaction Partner: ESR1, BRCA1, SUMO2, RPA3, RPA2, RPA1, REV1, POLK, DPYSL3, ATP6V1B2, CUL2, XRCC5, SUPT5H, STAT3, ST13, PDE3A, NRD1, JUP, XRCC6, SEC23A, HDAC6, PCNA, MSH3, MSH6, ERCC4, ERCC1, gag-pol, UBC, SUPT16H, SEPT9, SRSF10, SRSF11, SART1, SMARCA5, TOP2B, SRSF7, SRSF5
Protein Size: 934 -
分子量
- 105 kDa
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基因ID
- 4436
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NCBI登录号
- NM_000251, NP_000242
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UniProt
- P43246
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途径
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
抗原
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