FZD4 抗体 (Middle Region)
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北京 101111
Quick Overview for FZD4 抗体 (Middle Region) (ABIN405393)
抗原
See all FZD4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- GITSGMWIWS AKTLHTWQKC SNRLVNSGKV KREKRGNGWV KPGKGSETVV
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预测反应
- Cow: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against FZD4. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human FZD4
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anti-Frizzled Family Receptor 4 (FZD4) (AA 37-222) antibody
FZD4 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 2F3A7 unconjugated
anti-Frizzled Family Receptor 4 (FZD4) (Middle Region) antibodyFZD4 适用: 人, 小鼠, 大鼠, Cow, 马, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 4 (FZD4) antibodyFZD4 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 4 (FZD4) (AA 37-222) antibodyFZD4 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 4 (FZD4) (AA 107-206) antibodyFZD4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3G7 unconjugated
anti-Frizzled Family Receptor 4 (FZD4) (C-Term) antibodyFZD4 适用: 人, 小鼠, 大鼠, Pig, Cow, 犬, 小鸡, 马, 豚鼠, 猴, Bat, 兔 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 4 (FZD4) (C-Term) antibodyFZD4 适用: 人, 小鼠, 大鼠, Pig, Cow, 犬, 小鸡, 马, 猴, Hamster, Bat, 兔 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 4 (FZD4) (N-Term) antibodyFZD4 适用: 人, 大鼠, Cow, 犬, 猴, Hamster IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 4 (FZD4) (AA 151-250) antibodyFZD4 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 4 (FZD4) antibodyFZD4 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 537 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Impact of laminitis on the canonical Wnt signaling pathway in basal epithelial cells of the equine digital laminae." in: PLoS ONE, Vol. 8, Issue 2, pp. e56025, (2013) (PubMed).
: "A unique combination of male germ cell miRNAs coordinates gonocyte differentiation." in: PLoS ONE, Vol. 7, Issue 4, pp. e35553, (2012) (PubMed).
: "Spatio-temporal expression pattern of frizzled receptors after contusive spinal cord injury in adult rats." in: PLoS ONE, Vol. 7, Issue 12, pp. e50793, (2012) (PubMed).
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: "Impact of laminitis on the canonical Wnt signaling pathway in basal epithelial cells of the equine digital laminae." in: PLoS ONE, Vol. 8, Issue 2, pp. e56025, (2013) (PubMed).
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- FZD4 (Frizzled Family Receptor 4 (FZD4))
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别名
- FZD4
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背景
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FZD4 is a member of the frizzled family. Members of this family are seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence.This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: EVR1, FEVR, FZD4S, Fz-4, FzE4, GPCR, MGC34390, CD344
Protein Interaction Partner: UBC, NDP, ZNRF3, BAG6, MAGI3, DLG2, DLG4, DVL2, DLG1, ARRB2,
Protein Size: 537 -
分子量
- 60 kDa
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基因ID
- 8322
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NCBI登录号
- NM_012193, NP_036325
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UniProt
- Q9ULV1
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途径
- WNT signaling, Hormone Transport, Sensory Perception of Sound
抗原
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