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P2RX7 抗体 (N-Term)

P2RX7 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2776335
发货至: 中国
  • 抗原 See all P2RX7 抗体
    P2RX7 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7))
    抗原表位
    • 15
    • 7
    • 6
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 47
    • 39
    • 11
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠
    宿主
    • 54
    • 5
    • 2
    • 1
    克隆类型
    • 55
    • 7
    多克隆
    标记
    • 33
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This P2RX7 antibody is un-conjugated
    应用范围
    • 50
    • 25
    • 21
    • 13
    • 13
    • 10
    • 10
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    IQSMNYGTIK WFFHVIIFSY VCFALVSDKL YQRKEPVISS VHTKVKGIAE
    预测反应
    Cow: 93%, Dog: 79%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 93%
    产品特性
    This is a rabbit polyclonal antibody against P2RX7. It was validated on Western Blot and immunohistochemistry.
    纯化方法
    Protein A purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human P2RX7
    Top Product
    Discover our top product P2RX7 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 595 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Schneider, Glaser, Lameu, Abdelbaset-Ismail, Sellers, Moniuszko, Ulrich, Ratajczak: "Extracellular nucleotides as novel, underappreciated pro-metastatic factors that stimulate purinergic signaling in human lung cancer cells." in: Molecular cancer, Vol. 14, pp. 201, (2015) (PubMed).

  • 抗原
    P2RX7 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7))
    别名
    P2RX7 (P2RX7 产品)
    背景
    The product P2RX7 belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression.
    Alias Symbols: P2X7
    Protein Interaction Partner: KRTAP10-8, KRT31, TM9SF1, CASK, EFNB3, EMP3, PANX1, SVIL, ACTB,
    Protein Size: 595
    分子量
    69 kDa
    基因ID
    5027
    UniProt
    Q99572
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Vesicle Exocytosis
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