CCT4 抗体 (C-Term)
Quick Overview for CCT4 抗体 (C-Term) (ABIN2775694)
抗原
See all CCT4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- AFADAMEVIP STLAENAGLN PISTVTELRN RHAQGEKTAG INVRKGGISN
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预测反应
- Cow: 93%, Dog: 93%, Goat: 79%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%, Yeast: 100%, Zebrafish: 93%
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产品特性
- This is a rabbit polyclonal antibody against CCT4. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human CCT4
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 539 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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DYX1C1 is required for axonemal dynein assembly and ciliary motility. ..." in: Nature genetics, Vol. 45, Issue 9, pp. 995-1003, (2013) (PubMed).
: "Reconstitution of the human chaperonin CCT by co-expression of the eight distinct subunits in mammalian cells." in: Protein expression and purification, Vol. 82, Issue 1, pp. 61-9, (2012) (PubMed).
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DYX1C1 is required for axonemal dynein assembly and ciliary motility. ..." in: Nature genetics, Vol. 45, Issue 9, pp. 995-1003, (2013) (PubMed).
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- CCT4 (Chaperonin Containing TCP1, Subunit 4 (Delta) (CCT4))
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别名
- CCT4
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背景
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The CCT (chaperonin containing TCP-1) complex functions as a molecular chaperone in the eukaryotic cytosol. CCT4 interacts with human cyclin E which has been implicated in positive control of the G1/S phase transition.
Alias Symbols: SRB, Cctd, CCT-DELTA
Protein Interaction Partner: HUWE1, TP53, FUS, CDC20, NEDD1, TUBG1, LGALS3BP, UBC, STAU1, MDM2, RFWD2, VRK2, PRPF40A, CCT7, USP9X, VARS, CCT3, CCT6A, FBXO6, UBD, FBXW4, CDK9, CDK5, CDK2, CD81, IGSF8, HDAC11, HDAC3, RPS6KA1, ILK, ICAM1, PAN2, VCAM1, PPP5C, PEX14, NOS2, US3, FAM86B2, C
Protein Size: 539 -
分子量
- 58 kDa
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基因ID
- 10575
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NCBI登录号
- NM_006430, NP_006421
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UniProt
- Q53QP9
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途径
- Embryonic Body Morphogenesis
抗原
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