DMBT1 抗体 (N-Term)
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北京 101111
Quick Overview for DMBT1 抗体 (N-Term) (ABIN2775367)
抗原
See all DMBT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- SWSTPSPDTL PTITLPASTV GSESSLALRL VNGGDRCQGR VEVLYRGSWG
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预测反应
- Human: 100%
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产品特性
- This is a rabbit polyclonal antibody against DMBT1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human DMBT1
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anti-Deleted in Malignant Brain Tumors 1 (DMBT1) (AA 1701-1785) antibody
DMBT1 适用: 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Deleted in Malignant Brain Tumors 1 (DMBT1) (AA 2008-2413) antibodyDMBT1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Deleted in Malignant Brain Tumors 1 (DMBT1) antibodyDMBT1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Deleted in Malignant Brain Tumors 1 (DMBT1) (AA 2160-2192) antibodyDMBT1 适用: 大鼠 WB 宿主: 兔 Polyclonal RB53896 unconjugated
anti-Deleted in Malignant Brain Tumors 1 (DMBT1) (N-Term) antibodyDMBT1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 2413 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- DMBT1 (Deleted in Malignant Brain Tumors 1 (DMBT1))
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别名
- DMBT1
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背景
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Loss of sequences from human chromosome 10q has been associated with the progression of human cancers. The gene DMBT1 was originally isolated based on its deletion in a medulloblastoma cell line. DMBT1 is expressed with transcripts of 6.0, 7.5, and 8.0 kb in fetal lung and with one transcript of 8.0 kb in adult lung, although the 7.5 kb transcript has not been characterized. The DMBT1 protein is a glycoprotein containing multiple scavenger receptor cysteine-rich (SRCR) domains separated by SRCR-interspersed domains (SID). Transcript variant 2 (8.0 kb) has been shown to bind surfactant protein D independently of carbohydrate recognition. This indicates that DMBT1 may not be a classical tumor supressor gene, but rather play a role in the interaction of tumor cells and the immune system.
Alias Symbols: GP340, MGC164738, muclin
Protein Interaction Partner: CDK6, COPS6, SUMO2, UBC, PARD6B, SFTPD, SFTPA1,
Protein Size: 2413 -
分子量
- 258 kDa
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基因ID
- 1755
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NCBI登录号
- NM_007329, NP_015568
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UniProt
- Q9UGM3
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途径
- Activation of Innate immune Response
抗原
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