RAD23A 抗体 (N-Term)
Quick Overview for RAD23A 抗体 (N-Term) (ABIN2775295)
抗原
See all RAD23A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- VPSSGSSGRE EDAASTLVTG SEYETMLTEI MSMGYERERV VAALRASYNN
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预测反应
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against RAD23A. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human RAD23A
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 363 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- RAD23A (RAD23 Homolog A (RAD23A))
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别名
- RAD23A
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背景
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RAD23A is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in nucleotide excision repair (NER). This protein was shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, as well as with ubiquitin protein ligase E6AP, and thus suggests that this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in nucleotide excision repair (NER). This protein was shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, as well as with ubiquitin protein ligase E6AP, and thus suggests that this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.
Alias Symbols: HHR23A, MGC111083
Protein Interaction Partner: USP25, ZBTB44, TRIP6, TRAF5, TRAF2, ZBTB8A, ANKRD40, FAM188A, TRIM54, NGLY1, CEP250, CEP76, UBC, SHFM1, vpr, XPC, DCTPP1, OGFOD1, UBA6, UBE2R2, TRNT1, HERC4, NT5C2, FKBP9, PCNA, HEXA, CDC34, GNPDA1, GTF3C4, USP5, WARS, TBCE, PYGL, PARP1, SH3RF2, PARK2, SQ
Protein Size: 363 -
分子量
- 40 kDa
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基因ID
- 5886
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NCBI登录号
- NM_005053, NP_005044
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UniProt
- P54725
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途径
- DNA Damage Repair
抗原
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